Merck
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A4403

Sigma-Aldrich

L -抗坏血酸

powder, suitable for cell culture, γ-irradiated

Synonym(s):
维他命C, 抗坏血病因子, 维生素C
Empirical Formula (Hill Notation):
C6H8O6
CAS Number:
Molecular Weight:
176.12
Beilstein:
84272
EC 号:
MDL编号:
PubChem化学物质编号:
NACRES:
NA.75

生物来源

synthetic (organic)

质量水平

无菌性

γ-irradiated

形式

powder

分子量

Mw 176.12 g/mol

technique(s)

cell culture | insect: suitable
cell culture | mammalian: suitable
cell culture | plant: suitable

颜色

white to off-white

pH值(酸碱度)

1.0-2.5 (25 °C, 176 g/L in water)

mp

190-194 °C (dec.)

溶解性

H2O: 10 mg/mL

SMILES string

OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O

InChI

1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1

InChI key

CIWBSHSKHKDKBQ-JLAZNSOCSA-N

Gene Information

human ... SLC23A2(9962)

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L-Ascorbic acid powder, suitable for cell culture, γ-irradiated

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A4403

L -抗坏血酸

L-Ascorbic acid reagent grade, crystalline

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A7506

L -抗坏血酸

L-Ascorbic acid puriss. p.a., ACS reagent, reag. ISO, Ph. Eur., 99.7-100.5% (oxidimetric)

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33034

L -抗坏血酸

L-Ascorbic acid suitable for cell culture, suitable for plant cell culture, ≥98%

Sigma-Aldrich

A4544

L -抗坏血酸

form

powder

form

crystalline

form

solid

form

powder

pH

1.0-2.5 (25 °C, 176 g/L in water)

pH

1.0-2.5 (25 °C, 176 g/L in water)

pH

2.1-2.6 (20 °C, 5%)

pH

1.0-2.5 (25 °C, 176 g/L in water)

mp

190-194 °C (dec.)

mp

190-194 °C (dec.)

mp

190-194 °C (dec.)

mp

190-194 °C (dec.)

solubility

H2O: 10 mg/mL

solubility

water: soluble 50 mg/mL

solubility

water: soluble 176 g/L at 20 °C

solubility

water: soluble 50 mg/mL

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

biological source

synthetic (organic)

biological source

synthetic

biological source

synthetic

biological source

-

一般描述

L-抗坏血酸是一种不饱和γ-内酯环,含有与羰基相连的烯二醇构型(-COH =COH)。

应用

用于细胞培养,作为抗氧化剂和再生生育酚。
L-抗坏血酸已应用于:
  • 用于细胞生长的成骨补充剂
  • 作为分化介质的一个组成部分
  • 在WS-MSCs(沃纳综合征-间充质干细胞)中研究抗坏血酸对衰老缺陷的修复作用

生化/生理作用

L-抗坏血酸主要具有抗氧化性能。它保护植物免受氧化应激,保护哺乳动物免受与氧化应激相关的疾病。L-抗坏血酸主要对羟基自由基、超氧化物和单线态氧起保护作用。此外,它还还原膜连接的抗氧化剂α-生育酚(氧化形式)。L-抗坏血酸增强内皮依赖性血管舒张在各种疾病,包括糖尿病,冠状动脉疾病,高血压和慢性心力衰竭。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

个人防护装备

Eyeshields, Gloves, type N95 (US)


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