所有图片(2)

A5752

Sigma-Aldrich

肾上腺色素

别名:
3-羟基-1-甲基-5,6-二氢吲哚二酮
Empirical Formula (Hill Notation):
C9H9NO3
CAS号:
分子量:
179.17
EC 号:
MDL编号:
PubChem化学物质编号:
NACRES:
NA.47

质量水平

200

测定

>95% (HPLC)

形式

powder

应用

hematology: suitable
histology: suitable

εmax

3-4.5 at 485-490 nm in water
9.0-10.5 at 299-304 nm in water

特色行业

Diagnostic Assay Manufacturing

储存温度

−20°C

SMILES string

CN1CC(O)C2=CC(=O)C(=O)C=C12

InChI

1S/C9H9NO3/c1-10-4-9(13)5-2-7(11)8(12)3-6(5)10/h2-3,9,13H,4H2,1H3

InChI key

RPHLQSHHTJORHI-UHFFFAOYSA-N

应用

肾上腺色素已被用于研究其对大鼠心脏冠状动脉收缩的影响。

包装

25, 250 mg in glass insert

生化/生理作用

肾上腺色素是肾上腺素的氧化产物。它与心脏毒性有关。它是一种短寿命的细胞毒性分子,是用于杀死细菌的白细胞反应的一部分。肾上腺色素也被建议用以获得拟精神病作用。它可用于确定超氧化物歧化酶的活性。

其他说明

Scripps Center for Metabolomics(斯克里普斯代谢组学中心)独立生成的串联质谱数据,可以PDF格式查看或下载。 A5752.pdf 经过测试的代谢物在Scripps Center for Metabolomics(斯克里普斯代谢组学中心) METLIN代谢物数据库有重点介绍。更多信息请见sigma.com/metlin。

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

闪点(F)

Not applicable

闪点(C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

分析证书

原产地证书 (CofO)

Viviana S Fluxá et al.
Nature protocols, 3(8), 1270-1277 (2008-08-21)
The adrenaline test for enzymes is a colorimetric enzyme assay based on the quantification of periodate-sensitive reaction products such as 1,2-diols and 1,2-aminoalcohols by back-titration of the oxidant with adrenaline to produce adrenochrome as an easily detectable red product. The...
Adrenochrome-induced coronary artery constriction in the rat heart.
Karmazyn M, et al.
Journal of Pharmacology and Experimental Therapeutics, 219, 225-225 (1981)
Maria Luisa Genova et al.
Archives of biochemistry and biophysics, 447(2), 167-173 (2006-02-21)
Complex I in bovine heart submitochondrial particles catalyses the NADH-supported generation of superoxide anion; adrenaline is oxidised by superoxide to adrenochrome that, on its hand, is reduced by Complex I, thus establishing a redox cycle that amplifies the superoxide production....
Janna Shainsky et al.
Applied and environmental microbiology, 75(14), 4711-4719 (2009-05-26)
Enantiopure sulfoxides are prevalent in drugs and are useful chiral auxiliaries in organic synthesis. The biocatalytic enantioselective oxidation of prochiral sulfides is a direct and economical approach for the synthesis of optically pure sulfoxides. The selection of suitable biocatalysts requires...
Effect of Bacillus coagulans and B. firmus incorporated probiotic diet on Superoxide dismutase activity and catalase activity in Penaeus monodon.
Raghu P, et al.
World Scientific News, 44, 224-224 (2016)

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