Merck
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文件

A7699

Sigma-Aldrich

腺苷 5'-三磷酸 二钠盐 水合物

BioXtra, ≥99% (HPLC), from microbial

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别名:
ATP 二钠盐
Empirical Formula (Hill Notation):
C10H14N5Na2O13P3 · xH2O
CAS号:
34369-07-8
分子量:
551.14 (anhydrous basis)
EC 号:
213-579-1
MDL编号:
MFCD00150755
eCl@ss:
32160414
PubChem化学物质编号:
24891270
NACRES:
NA.51

生物来源

microbial

质量水平

300

产品线

BioXtra

检测方案

≥99% (HPLC)

形式

powder

杂质

≤0.1% inorganic P
≤3% solvent content

pKa 

(1) 4.0, (2) 6.5

溶解性

H2O: 50 mg/mL, clear, colorless

痕量阴离子

chloride (Cl-): ≤0.05%

痕量阳离子

Al: ≤0.005%
Ca: ≤0.01%
Cu: ≤0.001%
Fe: ≤0.05%
K: ≤0.01%
Mg: ≤0.005%
NH4+: ≤0.05%
Pb: ≤0.001%
Zn: ≤0.0005%

λmax

259 nm

储存温度

−20°C

SMILES string

O.[Na+].[Na+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]3O

InChI

1S/C10H16N5O13P3.2Na.H2O/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20;;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;;1H2/q;2*+1;/p-2/t4-,6-,7-,10-;;;/m1.../s1

InChI key

NTBQNWBHIXNPRU-MSQVLRTGSA-L

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此商品
A3377A26209A1852
Adenosine 5′-triphosphate disodium salt hydrate BioXtra, ≥99% (HPLC), from microbial

Sigma-Aldrich

A7699

腺苷 5'-三磷酸 二钠盐 水合物

Adenosine 5′-triphosphate disodium salt hydrate Grade II, ≥97% (HPLC), crystalline, from microbial

Sigma-Aldrich

A3377

腺苷 5'-三磷酸 二钠盐 水合物

Adenosine 5′-triphosphate disodium salt hydrate 99%

Sigma-Aldrich

A26209

腺苷 5'-三磷酸 二钠盐 水合物

Adenosine 5′-triphosphate (ATP) disodium salt hydrate vial of 30 mg

Sigma-Aldrich

A1852

腺苷 5′-三磷酸腺苷 (ATP) 二钠盐 水合物

assay

≥99% (HPLC)

assay

≥97% (HPLC)

assay

99%

assay

≥99% (HPLC)

form

powder

form

crystalline

form

-

form

powder

solubility

H2O: 50 mg/mL, clear, colorless

solubility

H2O: 50 mg/mL

solubility

-

solubility

water: 50 mg/mL, clear, colorless

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

−20°C

product line

BioXtra

product line

-

product line

-

product line

-

应用

腺苷5γ-三磷酸腺苷(ATP)是体内能量储存和代谢的中心成分。 ATP应用于许多细胞过程、呼吸、生物合成反应、运动和细胞分裂。ATP是许多激酶的底物，这些激酶参与细胞信号和腺苷酸环化酶(s)，产生第二个信使 cAMP。 ATP提供代谢能量来驱动代谢泵。 ATP在一系列酶促反应中充当辅酶。

生化/生理作用

P2 嘌呤能激动剂；增加 Ca2+-激活的 K+ 通道的活性；ATP-依赖酶系统的底物

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(F)

Not applicable

闪点(C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type N95 (US)

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腺苷5′-三磷酸 二钠盐 三水合物

Stefan P Mortensen et al.
The Journal of physiology, 589(Pt 7), 1847-1857 (2011-02-09)
Intraluminal ATP could play an important role in the local regulation of skeletal muscle blood flow, but the stimuli that cause ATP release and the levels of plasma ATP in vessels supplying and draining human skeletal muscle remain unclear. To
Mark W Gorman et al.
American journal of physiology. Heart and circulatory physiology, 299(6), H1981-H1989 (2010-09-21)
The adenine nucleotide hypothesis postulates that the ATP released from red blood cells is broken down to ADP and AMP in coronary capillaries and that ATP, ADP, and AMP act on purinergic receptors on the surface of capillary endothelial cells.
Shaima'a Hamarsheh et al.
Nature communications, 11(1), 1659-1659 (2020-04-05)
Oncogenic Ras mutations occur in various leukemias. It was unclear if, besides the direct transforming effect via constant RAS/MEK/ERK signaling, an inflammation-related effect of KRAS contributes to the disease. Here, we identify a functional link between oncogenic KrasG12D and NLRP3
Marc Clement et al.
Arteriosclerosis, thrombosis, and vascular biology, 39(8), 1645-1651 (2019-06-07)
MARK4 (microtubule affinity-regulating kinase 4) regulates NLRP3 (nucleotide-binding oligomerization domain, leucine-rich repeat, and pyrin domain containing 3) inflammasome activation. The aim of the study is to examine the role of MARK4 in hematopoietic cells during atherosclerosis. We show increased MARK4
Alexander Puzenko et al.
The Journal of chemical physics, 137(19), 194502-194502 (2012-11-28)
In this, the third part of our series on the dielectric spectrum symmetrical broadening of water, we consider the nucleotide aqueous solutions. Where in Parts I [E. Levy et al., J. Chem. Phys. 136, 114502 (2012)] and II [E. Levy
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实验方案

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Separation of Adenosine 5′-triphosphate disodium salt hydrate, BioXtra, ≥99% (HPLC), from microbial; Adenosine 5′-diphosphate sodium salt, bacterial, ≥95% (HPLC); 2′-Deoxyadenosine 5′-monophosphate, Sigma Grade, 98-100%

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