Merck

A9165

Sigma-Aldrich

N-乙酰基-L-半胱氨酸

suitable for cell culture, BioReagent

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别名:
LNAC, NAC
线性分子式:
HSCH2CH(NHCOCH3)CO2H
CAS号:
分子量:
163.19
Beilstein:
1724426
EC 号:
MDL编号:
PubChem化学物质编号:
NACRES:
NA.26

产品线

BioReagent

质量水平

检测方案

≥99% (TLC)

形式

powder

technique(s)

cell culture | mammalian: suitable

颜色

white to off-white

mp

106-108 °C (lit.)

溶解性

H2O: 100 mg/mL (with heating)

储存温度

2-8°C

SMILES string

CC(=O)N[C@@H](CS)C(O)=O

InChI

1S/C5H9NO3S/c1-3(7)6-4(2-10)5(8)9/h4,10H,2H2,1H3,(H,6,7)(H,8,9)/t4-/m0/s1

InChI key

PWKSKIMOESPYIA-BYPYZUCNSA-N

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此商品
PHR10981009005A0150000
N-Acetyl-L-cysteine suitable for cell culture, BioReagent

Sigma-Aldrich

A9165

N-乙酰基-L-半胱氨酸

Essential+ Grade
N-Acetyl-L-cysteine Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1098

N-乙酰基-L-半胱氨酸

-
Acetylcysteine United States Pharmacopeia (USP) Reference Standard

USP

1009005

乙酰半胱氨酸

-
Acetylcysteine European Pharmacopoeia (EP) Reference Standard

A0150000

乙酰半胱氨酸

-
assay

≥99% (TLC)

assay

-

assay

-

assay

-

form

powder

form

-

form

-

form

-

technique(s)

cell culture | mammalian: suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

-

color

white to off-white

color

-

color

-

color

-

mp

106-108 °C (lit.)

mp

106-108 °C (lit.)

mp

106-108 °C (lit.)

mp

106-108 °C (lit.)

应用

N-乙酰-L-半胱氨酸已被用作小鼠肠道干细胞培养的肠道基础培养基的组成部分,也被用作膨胀培养基的组成部分。

生化/生理作用

抗氧化剂和黏液溶解剂(mucolytic agent)。增加细胞池的自由基清除剂。 据报道可防止神经细胞凋亡,但会诱导平滑肌细胞凋亡。抑制HIV复制。可作为微粒体谷胱甘肽转移酶的底物。

通常也和此产品一起购买

产品编号
说明
价格

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2

储存分类代码

13 - Non Combustible Solids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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Acetylcysteine British Pharmacopoeia (BP) Reference Standard

BP907

乙酰半胱氨酸

Acetylcysteine United States Pharmacopeia (USP) Reference Standard

USP

1009005

乙酰半胱氨酸

Acetylcysteine European Pharmacopoeia (EP) Reference Standard

A0150000

乙酰半胱氨酸

N-Acetyl-L-cysteine Mucolytic agent and thiol-based antioxidant that has a protective effect against oxygen free radicals in early septic shock.

Millipore

106425

N-乙酰基-L-半胱氨酸

Isolation, Culture, and Maintenance of Mouse Intestinal Stem Cells
Kevin P. O?Rourke
Bio-protocol, 6(4), e1733-e1733 (2016)
Derivation and long-term expansion of human endometrial and decidual organoids
Margherita Turco
Protocol Exchange, 2639-2644 (2017)
Meritxell Huch et al.
Nature, 494(7436), 247-250 (2013-01-29)
The Wnt target gene Lgr5 (leucine-rich-repeat-containing G-protein-coupled receptor 5) marks actively dividing stem cells in Wnt-driven, self-renewing tissues such as small intestine and colon, stomach and hair follicles. A three-dimensional culture system allows long-term clonal expansion of single Lgr5(+) stem
Suzanne M Cloonan et al.
Journal of medicinal chemistry, 58(11), 4494-4505 (2015-05-12)
Ruthenium polypyridyl complexes show great promise as new photodynamic therapy (PDT) agents. However, a lack of detailed understanding of their mode of action in cells poses a challenge to their development. We have designed a new Ru(II) PDT candidate that
Yuval Samuni et al.
Biochimica et biophysica acta, 1830(8), 4117-4129 (2013-04-27)
N-acetylcysteine (NAC) has been in clinical practice for several decades. It has been used as a mucolytic agent and for the treatment of numerous disorders including paracetamol intoxication, doxorubicin cardiotoxicity, ischemia-reperfusion cardiac injury, acute respiratory distress syndrome, bronchitis, chemotherapy-induced toxicity

商品

Importance and uses of cysteine in serum-free eukaryotic, including hybridoma and Chinese Hamster Ovary (CHO) cell, cultures

Oxidative stress is mediated, in part, by reactive oxygen species produced by multiple cellular processes and controlled by cellular antioxidant mechanisms such as enzymatic scavengers or antioxidant modulators. Free radicals, such as reactive oxygen species, cause cellular damage via cellular.

氧化应激,在一部分上,是由多种细胞过程产生的活性氧介导,并由诸如酶清除剂或抗氧化剂调节剂等细胞抗氧化剂机制所控制的。自由基,如活性氧,会通过细胞引起细胞损伤。

Organoid culture products to generate tissue and stem cell derived 3D brain, intestinal, gut, lung and cancer tumor organoid models.

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Chromatograms

application for HPLC

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