A9667

Sigma-Aldrich

抗 人 IgE(ε-链特异性)-过氧物酶 山羊抗

IgG fraction of antiserum, buffered aqueous solution

MDL number:
NACRES:
NA.46

Quality Level

biological source

goat

antibody form

IgG fraction of antiserum

antibody product type

secondary antibodies

clone

polyclonal

form

buffered aqueous solution

application(s)

direct ELISA: 1:2,000
dot blot: 1:10,000 (chemiluminescent)

conjugate

peroxidase conjugate

shipped in

dry ice

storage temp.

−20°C

General description

IgE是糖蛋白抗体,可调节过敏和感染产生的免疫应答。这些免疫球蛋白被认为介导I型超敏反应 。IgE水平升高与高IgE综合征和过敏性哮喘有关。抗人IgE ε-链特异性过氧化物酶抗体与人IgE结合,也可抗人IgG、Bence Jones蛋白 κ 和 λ 骨髓瘤蛋白。
免疫球蛋白E(IgE)属于免疫球蛋白家族,由恒定(C)区中的艾普西隆(epsilon)(ε)重链组成。 IgE是在恒定区有额外结构域的单体结构。

Immunogen

从人骨髓瘤血清中纯化的 IgE

Application

山羊抗人IgE(ε-链特异性)过氧化物酶抗体用于IgE 免疫印迹 和 Western 印迹,分析 IgE 结合效率。

Physical form

溶于0.01M磷酸盐缓冲液,pH 7.4,含有0.05% MIT

Preparation Note

采用 Avrameas,S.等人 Scand J. Immunol .,8,增刊,7, 7 (1978) 描述的两步戊二醛法制备。

Disclaimer

除非我们的产品目录或产品随附的其他公司文件中另有说明,否则我们的产品仅用于研究用途,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、体外或体内治疗用途或任何类型的人类或动物消费或应用。

Pictograms

Health hazard

Signal Word

Danger

Hazard Statements

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

分析证书
原产地证书 (CofO)
Amita Misra et al.
GM crops & food, 3(4), 273-282 (2012-06-30)
Genetically modified (GM) mustard line (V4) with increased carotenoid content was compared with native mustard to find the difference in allergenic potential, if any. Simulated gastric fluid (SGF) digestibility of crude protein extract from GM as well as its native...
Marília Porto Oliveira Nunes et al.
PloS one, 14(4), e0214745-e0214745 (2019-04-18)
Given the growing incidence and prevalence of life-threatening food allergies, health concerns have raised new perspectives for in vivo and in vitro diagnostic methodologies, pointing to saliva as a promising material, already used to diagnose other pathologies. Based on the...
Alok Kumar Verma et al.
Toxicology letters, 210(1), 24-33 (2012-01-31)
Allergy to chickpea or Garbanzo bean (Cicer arietinum) has been reported in the Indian population. Little information is found regarding allergenic events involved in the chickpea allergy; therefore, chickpea allergenicity assessment was undertaken. In vivo and ex vivo studies were...
Effects of different thermal processing methods on the structure and allergenicity of peanut allergen Ara h 1
Tian Y, et al.
Food Science & Nutrition, 6(6), 1706-1714 (2018)
Middleton's Allergy 2-Volume Set: Principles and Practice (2013)
技术文章
Antibody-based serology tests are useful in identifying subjects with an adaptive immune response to the SARS-CoV-2 virus. Anti-human immunoglobulin antibodies allow for quick and simple, yet reliable assays with easy readouts and can also be adapted for high-throughput screening.
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