KCNK10 (TREK2) codes for a potassium channel protein that is activated by 2-aminoethoxydiphenyl borate (2-APB). TREK2 is known to be expressed in normal and cancerous ovarian cells.
Rabbit Anti-KCNK10 antibody recognizes rabbit, human, mouse, rat, and canine KCNK10.
Synthetic peptide directed towards the C terminal region of human KCNK10
Rabbit Anti-KCNK10 antibody is suitable for western blot applications at a concentration of 1.4 μg/ml.
KCNK10 is one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The message for this gene is highly expressed in the kidney and pancreas. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations. The protein is stimulated strongly by arachidonic acid and to a lesser degree by membrane stretching, intracellular acidification, and general anaesthetics. Three transcript variants have been identified for this gene.
Synthetic peptide located within the following region: QGASEDNIINKFGSTSRLTKRKNKDLKKTLPEDVQKIYKTFRNYSLDEEK
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
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