AV42325

Sigma-Aldrich

Anti-PSG1 (AB1) antibody produced in rabbit

IgG fraction of antiserum

别名:
Anti-DHFRP2, Anti-Pregnancy specific β-1-glycoprotein 1, Anti-PSBG1, Anti-PBG1, Anti-FLJ90654, Anti-FLJ90598, Anti-CD66f, Anti-B1G1

biological source

rabbit

Quality Level

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

47 kDa

species reactivity

human

concentration

0.5 mg - 1 mg/mL

application(s)

immunohistochemistry: suitable
western blot: suitable

conjugate

unconjugated

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... PSG1(5669)

General description

Pregnancy-specific β 1-glycoproteins (PSGs), related to the carcinoembryonic antigen family, are major placental, syncytiotrophoblast derived, polypeptides also found in the bloodstream in late pregnancy. Pregnancy specific β-1-glycoprotein 1 (PSG1, B1G1, PBG1) is believe to have immunomodulatory, and proangiogenic roles during pregnancy. PSG1 together with HLA-E (human leukocyte antigen-E) may be involved in early implantation and development of the embryo.

Specificity

Anti-PSG1 (AB1) polyclonal antibody reacts with human pregnancy specific β-1-glycoprotein 1.

Immunogen

Synthetic peptide directed towards the N terminal region of human PSG1

Application

Anti-PSG1 (AB1) polyclonal antibody is used to tag pregnancy specific β-1-glycoprotein 1 for detection and quantitation by Western blotting and in plasma by immunohistochemical (IHC) techniques. It is used as a probe to determine the roles of pregnancy specific β-1-glycoprotein 1 in placenta and embryonic development.

Sequence

Synthetic peptide located within the following region: SGRETAYSNASLLIQNVTREDAGSYTLHIIKGDDGTRGVTGRFTFTLHLE

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

分析证书
原产地证书 (CofO)
Jun Qiu et al.
Biochimica et biophysica acta, 1840(7), 2244-2252 (2014-03-07)
Cellular nucleic acid binding protein (CNBP) has been implicated in vertebrate craniofacial development and in myotonic dystrophy type 2 (DM2) and sporadic inclusion body myositis (sIBM) human diseases by controlling cell proliferation and survival to mediate neural crest expansion. CNBP...
Deepti Malik et al.
Molecular cancer, 13, 175-175 (2014-07-20)
microRNAs (miRNAs) play both oncogenic and oncostatic roles in leukemia. However, the molecular details underlying miRNA-mediated regulation of their target genes in pediatric B- and T-cell acute lymphoblastic leukemias (ALLs) remain unclear. The present study investigated the relationship between miR-2909...
Shalmali Avinash Pradhan et al.
Nucleic acids research, 42(10), 6243-6255 (2014-04-22)
The TSC2 gene, mutated in patients with tuberous sclerosis complex (TSC), encodes a 200 kDa protein TSC2 (tuberin). The importance of TSC2 in the regulation of cell growth and proliferation is irrefutable. TSC2 in complex with TSC1 negatively regulates the...

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