Pregnancy-specific β 1-glycoproteins (PSGs), related to the carcinoembryonic antigen family, are major placental, syncytiotrophoblast derived, polypeptides also found in the bloodstream in late pregnancy. Pregnancy specific β-1-glycoprotein 1 (PSG1, B1G1, PBG1) is believe to have immunomodulatory, and proangiogenic roles during pregnancy. PSG1 together with HLA-E (human leukocyte antigen-E) may be involved in early implantation and development of the embryo.
Anti-PSG1 (AB1) polyclonal antibody reacts with human pregnancy specific β-1-glycoprotein 1.
Synthetic peptide directed towards the N terminal region of human PSG1
Anti-PSG1 (AB1) polyclonal antibody is used to tag pregnancy specific β-1-glycoprotein 1 for detection and quantitation by Western blotting and in plasma by immunohistochemical (IHC) techniques. It is used as a probe to determine the roles of pregnancy specific β-1-glycoprotein 1 in placenta and embryonic development.
Synthetic peptide located within the following region: SGRETAYSNASLLIQNVTREDAGSYTLHIIKGDDGTRGVTGRFTFTLHLE
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
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