Brambell receptor (FcRB, FcRn) is a neonatal Fc receptor that mediates transmission of immunity from mother to young perinatally across epithelial cells and plays a central role in IgG protection and homeostasis throughout life. Fc fragment of IgG, receptor, transporter, α (FCGRT) is the heavy (α) chain of FcRn an Fc receptor that structurally resembles the major histocompatibility complex class I molecule.
Anti-FCGRT polyclonal antibody reacts with pig, human, mouse, bovine, and canine the α subunit of the neonatal receptor FcRn.
The immunogen for anti-FCGRT antibody: synthetic peptide derected towards the N terminal of human FCGRT
Anti-FCGRT polyclonal antibody is used to tag Fc fragment of IgG, receptor, transporter, α protein for detection and quantitation by Western blotting and in cells and tissues by immunohistochemical (IHC) techniques. It is used as a probe to study the possible roles of Fc fragment of IgG, receptor, transporter, α in the function of neonatal Fc receptor, FcRB.
Synthetic peptide located within the following region: GWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLE
Lyophilized from PBS buffer with 2% sucrose
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