Merck
All Photos(5)

C1768

Sigma-Aldrich

胞嘧啶 β-D-呋喃阿拉伯糖苷

crystalline, ≥90% (HPLC)

Synonym(s):
阿糖胞苷, Ara-C, 阿糖胞嘧啶, 胞嘧啶阿拉伯糖苷, 阿拉伯糖胞嘧啶, (β-D-阿拉伯呋喃糖基)胞嘧啶
Empirical Formula (Hill Notation):
C9H13N3O5
CAS Number:
Molecular Weight:
243.22
Beilstein:
89175
EC 号:
MDL编号:
PubChem化学物质编号:
NACRES:
NA.77

质量水平

200

测定

≥90% (HPLC)

形式

crystalline

储存温度

2-8°C

SMILES string

NC1=NC(=O)N(C=C1)[C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2O

InChI

1S/C9H13N3O5/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16)/t4-,6-,7+,8-/m1/s1

InChI key

UHDGCWIWMRVCDJ-CCXZUQQUSA-N

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包装

100, 500 mg in poly bottle
1, 5 g in poly bottle

生化/生理作用

阿糖胞苷复合到 DNA 中后,可通过与导致 DNA 断裂的拓扑异构酶 I 形成可裂解复合物而抑制 DNA 的复制,但不会抑制 RNA 的合成。抗白血病制剂。

特点和优势

该化合物是细胞凋亡研究的特色产品。点击此处 ,查看更多细胞凋亡精选产品。想要了解有关生物活性小分子在其他研究领域应用的更多信息,请访问 sigma.com/discover-bsm

象形图

Exclamation markHealth hazard

警示用语:

Warning

危险声明

危险分类

Repr. 2 - Skin Sens. 1

储存分类代码

11 - Combustible Solids

WGK

WGK 3

个人防护装备

Eyeshields, Faceshields, Gloves, type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

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More Documents

Quotes and Ordering

Articles

Nucleotide Synthesis in Cancer Cells

Neoplastic cells are highly dependent on the de novo synthesis of nucleotides to maintain sufficient pools to support DNA replication and the production of RNA.

DNA损伤和修复

DNA损伤和修复机制对于维持DNA完整性至关重要。细胞DNA的损伤与突变、癌症发展等有关。

DNA Damage and Repair

DNA damage and repair mechanism is vital for maintaining DNA integrity. Damage to cellular DNA is involved in mutagenesis, the development of cancer among others.

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