D2438
二甲基亚砜
sterile-filtered, BioPerformance Certified, meets EP, USP testing specifications, suitable for hybridoma
别名:
DMSO, 甲基亚砜
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关于此项目
线性分子式:
(CH3)2SO
化学文摘社编号:
分子量:
78.13
Beilstein:
506008
EC號碼:
MDL號碼:
分類程式碼代碼:
12191502
PubChem物質ID:
NACRES:
NA.75
Bp:
189 °C (lit.)
等級
BioPerformance Certified
品質等級
agency
USP XXIV
meets EP testing specifications
meets USP testing specifications
蒸汽密度
2.7 (vs air)
蒸汽壓力
0.42 mmHg ( 20 °C)
無菌
sterile-filtered
形狀
liquid
自燃溫度
573 °F
expl. lim.
42 %, 63 °F
技術
cell culture | hybridoma: suitable
cryopreservation: suitable
雜質
≤0.1% water
顏色
colorless
折射率
n20/D 1.479 (lit.)
bp
189 °C (lit.)
mp
16-19 °C (lit.)
溶解度
H2O: miscible (completely)
密度
1.10 g/mL (lit.)
SMILES 字串
CS(C)=O
InChI
1S/C2H6OS/c1-4(2)3/h1-2H3
InChI 密鑰
IAZDPXIOMUYVGZ-UHFFFAOYSA-N
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一般說明
二甲基亚砜（DMSO）是一种非质子溶剂。不溶于水的治疗性和有毒分子通常溶于DMSO。液氮与诸如DMSO的冷冻保护剂结合使用是广泛使用的细胞保存方法。DMSO已用于制备多种分子的储备溶液，并同时也作为这些分子的对照。它已用于溶解迁移后细胞的细胞迁移试验。经BPC测试的DMSO也可满足生物技术和组织工程应用的要求。
應用
二甲基亚砜已被用在体内培养和诱导肝星状细胞（HSC）活化中的载体对照。它还被用于制备储备溶液，以研究阿魏酸（FA）对髓核（NP）细胞的细胞毒性。
特點和優勢
即用型无菌过滤产品，被方便地包装在隔垫螺帽琥珀色瓶中。 符合USP和EP检测的要求
免責聲明
在室温下容易过冷并缓慢重融。 固化产品可以通过加热至室温来重新液化，而不会损害产品。
儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
188.6 °F - closed cup
閃點（°C）
87 °C - closed cup
個人防護裝備
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
A Oguro-Ando et al.
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Human molecular genetics, 24(15), 4225-4237 (2015-05-03)
Splice modulation therapy has shown great clinical promise in Duchenne muscular dystrophy, resulting in the production of dystrophin protein. Despite this, the relationship between restoring dystrophin to established dystrophic muscle and its ability to induce clinically relevant changes in muscle
Claudia C Faria et al.
Cancer research, 75(1), 134-146 (2014-11-14)
Medulloblastoma is the most common malignant pediatric brain tumor, with metastases present at diagnosis conferring a poor prognosis. Mechanisms of dissemination are poorly understood and metastatic lesions are genetically divergent from the matched primary tumor. Effective and less toxic therapies
Phillip McDonagh et al.
Veterinary microbiology, 174(3-4), 438-447 (2014-12-04)
Feline infectious peritonitis (FIP), a feline coronavirus (FCoV) induced disease, is almost invariably fatal with median life expectancy measured in days. Current treatment options are, at best, palliative. The objectives of this study were to evaluate a panel of nineteen
Mike Clements et al.
Toxicological sciences : an official journal of the Society of Toxicology, 140(2), 445-461 (2014-05-09)
Human stem cell derived cardiomyocytes (hESC-CM) provide a potential model for development of improved assays for pre-clinical predictive drug safety screening. We have used multi-electrode array (MEA) analysis of hESC-CM to generate multi-parameter data to profile drug impact on cardiomyocyte
商品
用于细胞系冷冻保存的良好细胞库操作实践概述。
Overview of good cell banking practices for cell line cryopreservation purposes.
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