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product name
2',7'-二氯荧光素二乙酸酯, ≥97%
品質等級
化驗
≥97%
形狀
powder
儲存溫度
−20°C
SMILES 字串
CC(=O)Oc1cc2Oc3cc(OC(C)=O)c(Cl)cc3C(c2cc1Cl)c4ccccc4C(O)=O
InChI
1S/C24H16Cl2O7/c1-11(27)31-21-9-19-15(7-17(21)25)23(13-5-3-4-6-14(13)24(29)30)16-8-18(26)22(32-12(2)28)10-20(16)33-19/h3-10,23H,1-2H3,(H,29,30)
InChI 密鑰
PXEZTIWVRVSYOK-UHFFFAOYSA-N
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一般說明
2′,7′-二氯荧光素二乙酸酯是一种细胞可渗透非荧光探针。它可在细胞内脱酯化并经氧化转化为具有强荧光性的2′,7′-二氯荧光素。
The excitation wavelength is 504 nm and emission wavelength is 529 nm in ethanol. The use of DMSO as the solvent has not been determined, however various publications suggest that it is suitable.
應用
2′,7′-二氯荧光素二乙酸酯适用于：
- 敏感并快速定量活性氧，以响应氧化代谢
- 微孔板法，以检测吞噬细胞中的氧化产物
- 定量多孔髓样分化测定
适用于：敏感并快速定量活性氧，以响应氧化代谢；微孔板法，以检测吞噬细胞中的氧化产物；髓样分化定量多孔测定。
儲存和穩定性
本品应在-20℃下以粉末形式保存。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
個人防護裝備
Eyeshields, Gloves, type N95 (US)
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商品
氧化应激，在一部分上，是由多种细胞过程产生的活性氧介导，并由诸如酶清除剂或抗氧化剂调节剂等细胞抗氧化剂机制所控制的。自由基，如活性氧，会通过细胞引起细胞损伤。
Cellular oxidative stress is countered by enzymatic scavengers and antioxidant modulators against reactive oxygen species damage.
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