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E2129

Sigma-Aldrich

伊文思蓝

Dye content ≥75 %, Powder

别名:

Direct Blue 53

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About This Item

经验公式（希尔记法）:
C34H24N6Na4O14S4
CAS号:
314-13-6
分子量:
960.81
颜色索引号:
23860
EC 号:
206-242-5
MDL编号:
MFCD00004021
UNSPSC代码:
12171500
PubChem化学物质编号:
24894456
NACRES:
NA.47

产品名称

伊文思蓝, Dye content ≥75 %

表单

powder

质量水平

200

组成

Dye content, ≥75%

技术

titration: suitable

应用

diagnostic assay manufacturing
hematology
histology

储存温度

room temp

SMILES字符串

[Na+].[Na+].[Na+].[Na+].Cc1cc(ccc1\N=N\c2ccc3c(cc(c(N)c3c2O)S([O-])(=O)=O)S([O-])(=O)=O)-c4ccc(\N=N\c5ccc6c(cc(c(N)c6c5O)S([O-])(=O)=O)S([O-])(=O)=O)c(C)c4

InChI

1S/C34H28N6O14S4.4Na/c1-15-11-17(3-7-21(15)37-39-23-9-5-19-25(55(43,44)45)13-27(57(49,50)51)31(35)29(19)33(23)41)18-4-8-22(16(2)12-18)38-40-24-10-6-20-26(56(46,47)48)14-28(58(52,53)54)32(36)30(20)34(24)42;;;;/h3-14,41-42H,35-36H2,1-2H3,(H,43,44,45)(H,46,47,48)(H,49,50,51)(H,52,53,54);;;;/q;4*+1/p-4/b39-37+,40-38+;;;;

InChI key

ATNOAWAQFYGAOY-GPTZEZBUSA-J

基因信息

human ... PTPN1(5770) , PTPRF(5792)

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相关类别

一般描述

伊文思蓝（EB）C.I.23860是一种合成双偶氮染料，也称为T-1824和直接蓝53。水溶性较高的EB染料对血清白蛋白具有很强的亲和力，是一种高分子量蛋白质示踪剂。

应用

伊文思蓝是一种著名的重要染色剂，适用于组织学和荧光显微镜。伊文思蓝已用于检查细胞活力和研究血脑屏障(BBB)的渗透性。其他应用包括展示特定的垂体细胞类型、中性粒细胞质膜的选择性染色以及在荧光显微镜中作为一种猝灭剂抑制不必要的自体荧光。

生化/生理作用

伊文思蓝是一种非渗透染料。在质膜存在损伤时，染料可进入细胞质和核中并将它们染成蓝色。伊文思蓝可用于检查细胞的活力。它还可用于研究BBB（血脑屏障）的通透性。染料与白蛋白结合，从而表明BBB已分解为蛋白。

象形图

Health hazard
GHS08

警示用语：

Danger

危险声明

H350

危险分类

Carc. 1B

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
SHBR6277
SHBQ4846
SHBP1253
SHBP6688
SHBN6470

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