Merck
All Photos(3)

E6758

Sigma-Aldrich

乙二胺四乙酸

anhydrous, crystalline, BioReagent, suitable for cell culture

Synonym(s):
EDTA, Ethylenedinitrilotetraacetic acid, 亚乙基二次氮基四乙酸, 依地酸
Linear Formula:
(HO2CCH2)2NCH2CH2N(CH2CO2H)2
CAS Number:
Molecular Weight:
292.24
Beilstein:
1716295
EC 号:
MDL编号:
eCl@ss:
39030907
PubChem化学物质编号:
NACRES:
NA.25

等级

anhydrous

质量水平

200

产品线

BioReagent

测定

≥98.5%

形式

crystalline

technique(s)

cell culture | mammalian: suitable

mp

250 °C (dec.) (lit.)

溶解性

3  M NaOH: 100 mg/mL

密度

1.46 g/cm3 at 20 °C

痕量阳离子

C: 40.7-41.5%
N: 9.3-9.8%

SMILES string

OC(=O)CN(CCN(CC(O)=O)CC(O)=O)CC(O)=O

InChI

1S/C10H16N2O8/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20)

InChI key

KCXVZYZYPLLWCC-UHFFFAOYSA-N

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应用

乙二胺四乙酸已被用于:
  • 作为肽稀释缓冲液的组分,用于细胞内BH3(Bcl-2同源(BH)结构域)分析和验证[1]
  • 作为肝星状细胞(HSC)培养的培养基成分[2]
  • 作为眼组织蛋白质提取的匀浆缓冲液的组分[3]
  • 用于阻止裂解缓冲液中的核酸酶反应[4]

包装

100, 500 g in poly bottle

生化/生理作用

乙二胺四乙酸(EDTA)是一种抗凝血剂,主要用于预防血液样本凝结。[5]EDTA可引发血小板聚集,导致假性血小板减少症。[6]EDTA和四环素可一起用作根面处理剂并用于缓解牙龈感染。[5]EDTA-四环素治疗可降低动脉粥样硬化中的冠状动脉钙水平。[7]EDTA二钠钙给药可有效减缓慢性肾病的进展。[8]

象形图

Exclamation mark

警示用语:

Warning

危险声明

预防措施声明

危险分类

Eye Irrit. 2

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(F)

Not applicable

闪点(C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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