推荐产品
生物源
wheat
品質等級
形狀
powder
技術
enzyme immunoassay: suitable
flow cytometry: suitable
InChI
1S/C29H41N7O9/c30-18(15-16-5-7-17(37)8-6-16)27(42)35-13-1-3-21(35)25(40)33-19(9-11-23(31)38)28(43)36-14-2-4-22(36)26(41)34-20(29(44)45)10-12-24(32)39/h5-8,18-22,37H,1-4,9-15,30H2,(H2,31,38)(H2,32,39)(H,33,40)(H,34,41)(H,44,45)
InChI 密鑰
HZWWPUTXBJEENE-UHFFFAOYSA-N
基因資訊
wheat ... Gli-Z1(100682397) , pqn5(543384)
正在寻找类似产品? 访问 产品对比指南
一般說明
谷蛋白由醇溶蛋白和谷蛋白两个醇溶蛋白家族组成。醇溶蛋白是一种疏水性很强的糖蛋白，溶解性极差。醇溶蛋白可进一步细分为 α-醇溶蛋白类，γ-醇溶蛋白和 ω-醇溶蛋白（基于其在低 pH 下电泳时的迁移率顺序。
應用
小麦来源麦醇溶蛋白用于：
- 胃蛋白酶-胰蛋白酶消化，研究体外麦醇溶蛋白挑战对无麸质饮食（GFD）乳糜泻（CD）患者活检组织的影响
- 制备麦醇溶蛋白，用于抗麦醇溶蛋白抗体测定
- 作为标准品，通过流式细胞仪，定量皮克级的麦醇溶蛋白
生化／生理作用
麦醇溶蛋白包含富含谷氨酰胺和脯氨酸的单体蛋白质家族，其占小麦籽粒总蛋白质含量的 40-50%。 醇溶性麦醇溶蛋白与不溶于醇的谷蛋白聚集形成谷蛋白，这是小麦面团的结构和性质的原因。 麦醇溶蛋白还参与乳糜泻的发病机制，乳糜泻是一种自身免疫性疾病，其中人白细胞抗原 DQ2 和 DQ8 将胶质肽递呈至 T 细胞亚群，诱导促炎细胞因子的释放，进而诱导肠黏膜基质的降解和细胞死亡。B 细胞也被刺激产生谷蛋白特异性和转谷氨酰胺酶 2 (TG2) 特异性抗体，后者可能是由麦醇溶蛋白肽与 TG2 共价结合的呈递所致。
品質
粗品；来自小麦面筋
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Jean-Baptiste Domergue et al.
International journal of molecular sciences, 23(9) (2022-05-15)
Isotopic analyses of plant samples are now of considerable importance for food certification and plant physiology. In fact, the natural nitrogen isotope composition (δ15N) is extremely useful to examine metabolic pathways of N nutrition involving isotope fractionations. However, δ15N analysis
Claudio Rhyner et al.
Immunology, 110(2), 269-274 (2003-09-27)
Coeliac disease (CD), a gastrointestinal illness characterized by intestinal malabsorption, results from gluten intolerance accompanied with immunological responses towards gliadin, an ethanol-soluble protein fraction of wheat and other cereals. The role of gliadin in eliciting immune responses in CD is
Valentina Vaira et al.
Clinical science (London, England : 1979), 126(6), 417-423 (2013-09-26)
CD (coeliac disease) is a frequent autoimmune disorder of the small bowel, which is characterized by an immunological reaction against gluten and transglutaminase in genetically predisposed subjects. However, the molecular determinants underpinning CD pathogenesis are yet to be fully elucidated
Quantification of gliadin levels to the picogram level by flow cytometry
Capparelli R, et al.
Cytometry. Part A : the Journal of the International Society For Analytical Cytology, 63A(2), 108-113 (2005)
L J Chartrand et al.
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 157(5), 527-533 (1997-09-19)
To test the effectiveness of serologic antigliadin antibody (AGA) testing in predicting celiac disease in children. Prospective clinical assessment. Hôpital Sainte-Justine, montreal. A total of 176 children with possible celiac disease who were referred for duodenal biopsy between January 1992
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门