G5262

Supelco

GAPDH

standard for protein electrophoresis

别名:
D-甘油醛-3-磷酸:NAD+ 氧化还原酶(磷酸化), GAPDH, 甘油醛-3-磷酸脱氢酶 来源于兔肌肉
CAS号:
EC 号:
MDL编号:

质量水平

200

等级

for molecular biology

形式

powder

分子量

~36 kDa

包装

vial of 5 mg

应用

electrophoresis: suitable

储存温度

2-8°C

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相关类别

一般描述

甘油醛-3-磷酸脱氢酶(GAPDH)催化甘油醛-3-磷酸以转化为D-甘油酸-1,3-二磷酸,作为糖酵解途径的一部分。还发现,GAPDH在其他细胞过程中发挥作用,如转录、凋亡、氧化应激和内质网到高尔基体的迁移。

应用

GAPDH蛋白适合用作分子生物学应用的分子量标记和蛋白质标准,包括蛋白印迹和质谱测定。

生化/生理作用

甘油醛-3-磷酸脱氢酶催化甘油醛-3-磷酸转化为D-甘油酸-1,3-二磷酸,作为糖酵解途径的一部分。

storage_class_code

13 - Non Combustible Solids

WGK Germany

WGK 3

闪点(F)

Not applicable

闪点(C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

分析证书

原产地证书 (CofO)

Ling Ji et al.
Molecular therapy. Nucleic acids, 19, 546-561 (2020-01-14)
Long non-coding RNAs (lncRNAs) are crucial molecules in tumorigenesis and tumor growth in various human cancers, including colorectal cancer (CRC). Studies have revealed that lncRNAs can regulate cellular processes in cancers by interacting with proteins, for example RNA-binding proteins (RBPs)....
S A Ismail et al.
Acta crystallographica. Section D, Biological crystallography, 61(Pt 11), 1508-1513 (2005-10-22)
The crystal structure of human liver glyceraldehyde-3-phosphate dehydrogenase (GAPDH) has been determined. This structure represents the first moderate-resolution (2.5 A) and crystallographically refined (Rfree = 22.9%) human GAPDH structure. The liver GAPDH structure consists of a homotetramer, each subunit of...
Kati Juuti-Uusitalo et al.
Investigative ophthalmology & visual science, 54(5), 3510-3519 (2013-05-21)
Aquaporins (AQPs), a family of transmembrane water channel proteins, are essential for allowing passive water transport through retinal pigmented epithelial (RPE) cells. Even though human native RPE cells and immortalized human RPEs have been shown to express AQPs, the expression...
Wen-Wei Zhang et al.
Eukaryotic cell, 12(1), 70-77 (2012-11-06)
The initial 7 steps of the glycolytic pathway from glucose to 3-phosphoglycerate are localized in the glycosomes in Leishmania, including step 6, catalyzed by the enzyme glyceraldehyde-3-phosphate dehydrogenase (GAPDH). In L. donovani and L. mexicana, there exists a second GAPDH...
J E Welch et al.
Journal of andrology, 21(2), 328-338 (2000-03-14)
Although the process of glycolysis is highly conserved in eukaryotes, several glycolytic enzymes have unique structural or functional features in spermatogenic cells. We previously identified and characterized the mouse complementary DNA (cDNA) and a gene for 1 of these enzymes...

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