Merck

G8168

Sigma-Aldrich

G 418 二硫酸盐 溶液

50 mg/mL in H2O, 0.1 μm filtered, BioReagent, suitable for cell culture

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别名:
抗生素G418
经验公式(希尔记法):
C20H40N4O10 · 2H2SO4
分子量:
692.71
MDL编号:
PubChem化学物质编号:
NACRES:
NA.76

生物来源

Micromonospora echinospora

质量水平

无菌性

0.1 μm filtered

产品线

BioReagent

形式

solution

效能

50-60 mg per mL

分子量

692.7

包装

pkg of 10 and 100 mL

浓度

50 mg/mL in H2O

技术

cell culture | mammalian: suitable

杂质

endotoxin, tested

颜色

colorless

溶解性

H2O: 50 mg/mL, clear

抗生素抗菌谱

parasites

作用机制

protein synthesis | interferes

储存温度

2-8°C

SMILES字符串

OS(O)(=O)=O.OS(O)(=O)=O.CN[C@H]1[C@H](O)[C@@H](OC[C@@]1(C)O)O[C@H]2[C@H](N)C[C@H](N)[C@@H](O[C@H]3O[C@H]([C@H](C)O)[C@@H](O)[C@H](O)[C@H]3N)[C@@H]2O

InChI

1S/C20H40N4O10.2H2O4S/c1-6(25)14-11(27)10(26)9(23)18(32-14)33-15-7(21)4-8(22)16(12(15)28)34-19-13(29)17(24-3)20(2,30)5-31-19;2*1-5(2,3)4/h6-19,24-30H,4-5,21-23H2,1-3H3;2*(H2,1,2,3,4)/t6?,7-,8+,9+,10+,11-,12-,13-,14+,15+,16-,17-,18+,19-,20+;;/m0../s1

InChI key

UHEPSJJJMTWUCP-NKCAIAFTSA-N

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此商品
G1279G5013G418-RO
G 418 二硫酸盐 溶液 50 mg/mL in H2O, 0.1 μm filtered, BioReagent, suitable for cell culture

G8168

G 418 二硫酸盐 溶液

G 418 二硫酸盐 suitable for plant cell culture, BioReagent

G1279

G 418 二硫酸盐

G 418 二硫酸盐 potency: ≥720 μg per mg (dried basis)

G5013

G 418 二硫酸盐

G-418溶液 solution, =98% (TLC), suitable for transfection

G418-RO

G-418溶液

antibiotic activity spectrum

parasites

antibiotic activity spectrum

Gram-negative bacteria

antibiotic activity spectrum

Gram-negative bacteria

antibiotic activity spectrum

protozoa

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | plant: suitable

technique(s)

-

technique(s)

transfection: suitable

Quality Level

200

Quality Level

-

Quality Level

-

Quality Level

100

product line

BioReagent

product line

BioReagent

product line

-

product line

-

form

solution

form

powder

form

powder

form

solution

一般描述

化学结构:氨基糖苷类

应用

G418二硫酸盐是一种氨基糖苷类抗生素,其结构与庆大霉素相似,用于选择和维持原核和真核细胞。不同细胞系具有不同的筛选和维持最佳浓度。 细菌和藻类最多需要5 μg/mL而动物细胞则可能需要300-500 μg/mL。

生化/生理作用

作用机制:G418可通过抑制70S和80S核糖体的合成来阻止多肽合成和蛋白质延伸。

抗菌谱:G418可选择经iNOS启动子构建体和新霉素抗性基因稳定转染的细胞,并显示出对原生动物和蠕虫的活性。

注意

该产品在2-8°C下可稳定储存两年。

象形图

Health hazard

警示用语:

Danger

危险声明

危险分类

Resp. Sens. 1 - Skin Sens. 1

储存分类代码

12 - Non Combustible Liquids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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