G8769

Sigma-Aldrich

D -(+)-葡萄糖 溶液

45% in H2O, sterile-filtered, BioXtra, suitable for cell culture

Empirical Formula (Hill Notation):
C6H12O6
CAS号:
分子量:
180.16
Beilstein/REAXYS Number:
1281608
EC 号:
MDL编号:
PubChem化学物质编号:
NACRES:
NA.75

质量水平

200

无菌性

sterile-filtered

产品线

BioXtra

形式

solution

浓度

45% in H2O

应用

cell culture | mammalian: suitable

杂质

endotoxin, tested

SMILES string

OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1

InChI key

WQZGKKKJIJFFOK-DVKNGEFBSA-N

Gene Information

human ... PYGM(5837)

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一般描述

葡萄糖是活细胞生理过程中必不可少的能量货币。它可以用作糖蛋白、糖脂和糖胺聚糖前体。

应用

D-(+)-葡萄糖溶液可用作以下培养基补充剂:
  • 杜氏改良Eagle培养基(DMEM),用于培养 Flp-In  293 细胞
  • 大鼠脑冠状切片解剖培养基
  • 神经干细胞培养基,用于培养海马细胞

为细胞代谢提供主要的能量来源。

生化/生理作用

葡萄糖是体外条件下帮助哺乳动物细胞生长和存活的关键组成部分,对产量和质量而言至关重要。高代谢率有利于破骨细胞分化。葡萄糖水平可以调节肿瘤细胞的迁移和生长。HeLa细胞在低葡萄糖水平下显示出高迁移率。

RIDADR

NONH for all modes of transport

WGK Germany

WGK 1

闪点(F)

Not applicable

闪点(C)

Not applicable

分析证书

原产地证书 (CofO)

Glucose: an energy currency and structural precursor in articular cartilage and bone with emerging roles as an extracellular signaling molecule and metabolic regulator
Mobasheri A
Frontiers in Endocrinology, 3, 153-153 (2012)
High glucose and low specific cell growth but not mild hypothermia improve specific r-protein productivity in chemostat culture of CHO cells
Vergara M, et al.
Testing, 13(8), e0202098-e0202098 (2018)
Investigation of the Influence of Glucose Concentration on Cancer Cells by Using a Microfluidic Gradient Generator without the Induction of Large Shear Stress
Ishida T, et al.
Micromachines, 7(9), 155-155 (2016)
Protein kinase C activation causes neurite retraction via cyclin D 1 and p60-katanin increase in rat hippocampal neurons
Korulu S, et al.
The European Journal of Neuroscience, 37(10), 1610-1619 (2013)
Chad A Dumstorf et al.
Molecular cancer therapeutics, 9(12), 3158-3163 (2010-10-26)
Enzastaurin (LY317615.HCl) is currently in a phase III registration trial for diffuse large B-Cell lymphoma and numerous phase II clinical trials. Enzastaurin suppresses angiogenesis and induces apoptosis in multiple human tumor cell lines by inhibiting protein kinase C (PKC) and...
技术文章
Glucose metabolism is regulated by the opposing actions of insulin and glucagon. Insulin is released from pancreatic ß cells in response to high blood glucose levels and regulates glucose metabolism through its actions on muscle, liver, and adipose tissue.
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