H3911

SAFC

L-组氨酸

别名:
(S)-2-氨基-3-(4-咪唑基)丙酸, NSC 137773
Empirical Formula (Hill Notation):
C6H9N3O2
CAS号:
分子量:
155.15
Beilstein/REAXYS Number:
84088
EC 号:
MDL编号:
eCl@ss:
32160406
PubChem化学物质编号:
NACRES:
NA.26

生物来源

non-animal source

测定

≥98.5%

形式

crystalline powder

manufacturer/tradename

Ajinomoto

应用

cell culture | mammalian: suitable

杂质

endotoxin, heavy metals, trace metals, residual solvents, tested

mp

282 °C (dec.) (lit.)

溶解性

H2O: 50 mg/mL

适用性

suitable for manufacturing use

特色行业

Pharmaceutical (small molecule)

异质活性

cytotoxicity, tested

SMILES string

N[C@@H](Cc1c[nH]cn1)C(O)=O

InChI

1S/C6H9N3O2/c7-5(6(10)11)1-4-2-8-3-9-4/h2-3,5H,1,7H2,(H,8,9)(H,10,11)/t5-/m0/s1

InChI key

HNDVDQJCIGZPNO-YFKPBYRVSA-N

Gene Information

human ... CA1(759) , CA2(760)

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一般描述

To request documentation for this product, please contact Customer Support and select ‘Product Documentation′. Please note that access to the documentation for this product requires a confidentiality disclosure agreement.

应用

L-组氨酸是一种必需氨基酸。它用作细胞培养基组分,用于治疗性重组蛋白和单克隆抗体的商业生物制造。

生化/生理作用

组胺的前体,经组氨酸脱羧酶作用可生成组胺。

storage_class_code

11 - Combustible Solids

WGK Germany

WGK 1

闪点(F)

Not applicable

闪点(C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

分析证书

原产地证书 (CofO)

Urszula Kosinska Eriksson et al.
Science (New York, N.Y.), 340(6138), 1346-1349 (2013-06-15)
Aquaporins are membrane channels that facilitate the flow of water across biological membranes. Two conserved regions are central for selective function: the dual asparagine-proline-alanine (NPA) aquaporin signature motif and the aromatic and arginine selectivity filter (SF). Here, we present the...
Smriti Kala et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(16), 6022-6027 (2014-04-09)
The genome packaging reactions of tailed bacteriophages and herpes viruses require the activity of a terminase enzyme, which is comprised of large and small subunits. Phage genomes are replicated as linear concatemers composed of multiple copies of the genome joined...
Camilla Hofström et al.
Journal of medicinal chemistry, 56(12), 4966-4974 (2013-05-23)
Engineered affibody molecules can be used for high contrast in vivo molecular imaging. Extending a recombinantly produced HER2 binding affibody molecule with a hexa-histidine tag allows for convenient purification by immobilized metal-ion affinity chromatography and labeling with [(99m)Tc(CO)3](+) but increases...
Pawel Swietach et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(22), E2064-E2073 (2013-05-17)
Ca(2+) signaling regulates cell function. This is subject to modulation by H(+) ions that are universal end-products of metabolism. Due to slow diffusion and common buffers, changes in cytoplasmic [Ca(2+)] ([Ca(2+)]i) or [H(+)] ([H(+)]i) can become compartmentalized, leading potentially to...
H M Golder et al.
Journal of dairy science, 97(8), 5131-5150 (2014-06-03)
Ruminal bacterial community composition (BCC) and its associations with ruminal fermentation measures were studied in dairy heifers challenged with combinations of grain, fructose, and histidine in a partial factorial study. Holstein-Friesian heifers (n=30) were randomly allocated to 5 triticale grain-based...

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