Merck
所有图片(6)

H4001

Sigma-Aldrich

氢化可的松

≥98% (HPLC)

别名:
皮质醇, 11β,17α,21-三羟基孕甾-4-烯-3,20-二酮, 17-羟基皮质甾酮, 氢化泼尼松龙, 4-孕烯-11β,17α,21-三醇-3,20-二酮, 氢化皮质酮
Empirical Formula (Hill Notation):
C21H30O5
CAS号:
分子量:
362.46
Beilstein:
1354819
EC 号:
MDL编号:
PubChem化学物质编号:
NACRES:
NA.77

质量水平

300

生物来源

synthetic (organic)

无菌性

non-sterile

测定

≥98% (HPLC)

形式

powder

mp

211-214 °C (lit.)

溶解性

water: 0.28 g/L at 25 °C

application(s)

cell analysis

运输

ambient

储存温度

room temp

SMILES string

[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]4(C)[C@@]2([H])CC[C@]4(O)C(=O)CO

InChI

1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1

InChI key

JYGXADMDTFJGBT-VWUMJDOOSA-N

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包装

1, 5, 10, 25, 100 g in poly bottle

生化/生理作用

肾上腺皮质分泌的原发性糖皮质激素。消炎效果是皮质酮的三倍,但 Na2+ 保留性能比皮质酮低。

特点和优势

该化合物是受体分类及信号转导手册上核受体(类固醇)页面上的特色化合物。想要浏览手册的其他页面, 请单击此处

象形图

Health hazard

警示用语:

Danger

危险声明

危险分类

Repr. 1A - STOT RE 2

储存分类代码

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(F)

Not applicable

闪点(C)

Not applicable

个人防护装备

Eyeshields, Gloves, type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges

分析证书

请输入批号搜索分析证书(COA)。

原产地证书 (CofO)

请输入批号搜索原产地证书(COO)。

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The Journal of clinical endocrinology and metabolism, 99(5), 1665-1674 (2014-02-13)
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The American journal of psychiatry, 171(8), 872-880 (2014-05-17)
Differential effects of maternal and paternal posttraumatic stress disorder (PTSD) have been observed in adult offspring of Holocaust survivors in both glucocorticoid receptor sensitivity and vulnerability to psychiatric disorder. The authors examined the relative influences of maternal and paternal PTSD
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The benefits versus the risks of postnatal administration of steroids in preterm-born infants are still debatable. This review examines the literature on postnatal hydrocortisone treatment for chronic lung disease (CLD) in preterm-born infants with a particular focus on the effects
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Gut-derived hormones, such as GLP-1, have been proposed to relay information to the brain to regulate appetite. GLP-1 receptor agonists, currently used for the treatment of type 2 diabetes (T2DM), improve glycemic control and stimulate satiety, leading to decreases in

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