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Merck

H9262

Sigma-Aldrich

羟丙基 甲基纤维素

viscosity 80-120 cP, 2 % in H2O(20 °C)(lit.)

别名:

2-Hydroxypropyl methyl cellulose ether

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About This Item

CAS号:
MDL编号:
UNSPSC代码:
12352201
NACRES:
NA.56

表单

powder

分子量

~26 kDa

颜色

beige

粘度

80-120 cP, 2 % in H2O(20 °C)(lit.)

SMILES字符串

O3[C@H]([C@@H]([C@H]([C@@H]([C@H]3COCC(O)C)OCC(O)C)OCC(O)C)OCC(O)C)O[C@@H]4[C@H](O[C@H]([C@@H]([C@H]4OCC(O)C)OCC(O)C)OCC(O)C)COCC(O)C.O1[C@H]([C@@H]([C@H]([C@@H]([C@H]1COC)OC)OC)OC)O[C@@H]2[C@H](O[C@H]([C@@H]([C@H]2OC)OC)OC)COC

InChI key

PUSNGFYSTWMJSK-GSZQVNRLSA-N

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应用

水和非水系统的增稠剂、具有抗脂性的透明薄膜、粘合剂、润滑剂、空间稳定剂和保水剂。
(羟丙基)甲基纤维素作为增稠剂用于水性和非水性体系,是一种保水剂和空间稳定剂,透明薄膜具有抗油脂性。(羟丙基)甲基纤维素在设计延长肠道滞留时间的给药系统时被用于研究黏膜黏附,也被用于研究难水溶性药物的溶出速率的增强。

特点和优势

溶于水,加热后可逆凝胶化,非离子,不与离子组分络合,具有表面活性和抗酶活性。溶液为假塑性。

其他说明

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储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Deirdre M D'Arcy et al.
AAPS PharmSciTech, 20(2), 47-47 (2019-01-09)
Viscosity, influenced by medium composition, will affect the hydrodynamics of a dissolution system. Dissolution simulation methods are valuable tools to explore mechanistic dissolution effects, with an understanding of limitations of any simulation method essential to its appropriate use. The aims
Lucas Sievens-Figueroa et al.
International journal of pharmaceutics, 423(2), 496-508 (2011-12-20)
The design and feasibility of a simple process of incorporating stable nanoparticles into edible polymer films is demonstrated with the goal of enhancing the dissolution rate of poorly water soluble drugs. Nanosuspensions produced from wet stirred media milling (WSMM) were
Fernando Andrés et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(26), E2760-E2769 (2014-07-01)
In Arabidopsis thaliana environmental and endogenous cues promote flowering by activating expression of a small number of integrator genes. The MADS box transcription factor SHORT VEGETATIVE PHASE (SVP) is a critical inhibitor of flowering that directly represses transcription of these
Jeonghoon Han et al.
Aquatic toxicology (Amsterdam, Netherlands), 152, 308-317 (2014-05-13)
In this study, we investigated the effects of the water-accommodated fraction (WAF) of crude oil on the development and reproduction of the intertidal copepod Tigriopus japonicus through life-cycle experiments. Furthermore, we investigated the mechanisms underlying the toxic effects of WAF
Somayeh Bahrami et al.
Veterinary parasitology, 203(1-2), 43-50 (2014-03-19)
Fasciola gigantica is a parasitic helminth that predominantly infects the liver and bile ducts of cattle and causes great losses of cattle production in the southwestern regions of Iran. The purpose of the present study was to find out the

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