Merck
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文件

H9633

Sigma-Aldrich

L-同型半胱氨酸

≥95%

所有图片(4)
别名:
L-2-氨基-4-磺基丁酸
Empirical Formula (Hill Notation):
C4H9NO5S
CAS号:
14857-77-3
分子量:
183.18
MDL编号:
MFCD00066018
PubChem化学物质编号:
24895863
NACRES:
NA.32

质量水平

200

检测方案

≥95%
≥98% (TLC)

形式

powder

颜色

white to off-white

application(s)

cell analysis

SMILES string

N[C@@H](CCS(O)(=O)=O)C(O)=O

InChI

1S/C4H9NO5S/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H,8,9,10)/t3-/m0/s1

InChI key

VBOQYPQEPHKASR-VKHMYHEASA-N

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此商品
H6503M1126H4628
L-Homocysteic acid ≥95%

Sigma-Aldrich

H9633

L-同型半胱氨酸

L-Homocysteine thiolactone hydrochloride ≥98% (TLC)

Sigma-Aldrich

H6503

L-同型半胱氨酸硫内酯 盐酸盐

L-Methionine sulfoxide

Sigma-Aldrich

M1126

L -甲硫氨酸亚砜

DL-Homocysteine ≥95% (titration)

Sigma-Aldrich

H4628

DL-同型半胱氨酸

form

powder

form

powder

form

powder

form

powder

color

white to off-white

color

white

color

white to off-white

color

-

application(s)

cell analysis

application(s)

detection
peptide synthesis

application(s)

detection
peptide synthesis

application(s)

cell analysis
peptide synthesis

应用

L-同型半胱氨酸已被用于研究在神经系统中过氧化氢介导的生理和病理状态变化。

生化/生理作用

L-同型半胱氨酸（L-HCA）是NMDA（N-甲基-D-天冬氨酸）受体的一种内源性神经递质配体。它是谷氨酸的一种类似物，可竞争性抑制神经元中谷氨酸-半胱氨酸（xc-）反转运蛋白的功能，引起半胱氨酸摄取量下降。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(F)

Not applicable

闪点(C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

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货号
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25G
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Slide 1 of 8

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Seleno-DL-cystine powder

Sigma-Aldrich

S1650

硒代-DL-胱氨酸

Selenomethionine United States Pharmacopeia (USP) Reference Standard

USP

1611955

硒蛋氨酸

3-Amino-1-propanesulfonic acid 97%

Sigma-Aldrich

A76109

3-氨基-1-丙磺酸

DL-Homocysteine thiolactone hydrochloride ≥99.0% (AT)

Sigma-Aldrich

53530

3-氨基二氢噻吩-2-酮 盐酸盐

Seleno-L-cystine 95%

Sigma-Aldrich

545996

L-硒代胱胺基乙酸

Hemin from bovine, ≥90%

Sigma-Aldrich

H9039

氯化高铁血红素

S-(5′-Adenosyl)-L-homocysteine crystalline

Sigma-Aldrich

A9384

S-(5′-腺苷)-L-高半胱氨酸

L-Cysteine ≥97%, FG

Sigma-Aldrich

W326305

L-半胱氨酸

Hari H Subramanian et al.
The Journal of comparative neurology, 526(2), 229-242 (2017-09-07)
The nucleus retroambiguus (NRA) is a neuronal cell group in the medullary ventrolateral tegmentum, rostrocaudally between the obex and the first cervical spinal segment. NRA neurons are premotor interneurons with direct projections to the motoneurons of soft palate, pharynx, and
M Piraud et al.
Rapid communications in mass spectrometry : RCM, 19(22), 3287-3297 (2005-10-20)
Seventy-six compounds of biological interest for the diagnosis of inherited disorders of amino acids (AA) metabolism have previously been demonstrated to be detectable in positive mode electrospray ionisation tandem mass spectrometry (ESI-MS/MS), after separation by ion-pairing reversed-phase liquid chromatography (RPLC).
T Knöpfel et al.
Neuroscience letters, 81(1-2), 188-192 (1987-10-16)
The effects of ionophoretically applied L-homocysteate (L-HCA), L-glutamate (L-Glu) and N-methyl-D-aspartate (NMDA) were compared in rat neocortical neurons recorded intracellularly in vitro. The firing pattern and the time course of membrane depolarization induced by L-HCA resembled those of NMDA responses.
J W Olney et al.
Brain research bulletin, 19(5), 597-602 (1987-11-01)
L-Homocysteic acid (L-HCA) has been proposed as a natural transmitter at the N-methyl-D-aspartate (NMDA) subtype of excitatory amino acid receptor based on recent evidence that L-HCA occurs L-HCA occurs naturally in the mammalian CNS, is released from K+ stimulated brain
Danté T Johnson et al.
The Journal of biological chemistry, 294(32), 11969-11979 (2019-07-03)
Fast photochemical oxidation of proteins (FPOP) is a MS-based method that has proved useful in studies of protein structures, interactions, conformations, and protein folding. The success of this method relies on the irreversible labeling of solvent-exposed amino acid side chains
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