M0267

(+/-)-美沙酮 盐酸盐

powder, ≥98%

• 别名: 6-Dimethylamino-4,4-diphenylheptan-3-one hydrochloride
• 经验公式（希尔记法）: C₂₁H₂₇NO · HCl
• CAS Number: 1095-90-5
• 分子量: 345.91
• EC號碼: 214-140-7
• MDL號碼: MFCD00058014
• 分類程式碼代碼: 12352200
• PubChem物質ID: 24896546
• NACRES: NA.77

属性

• 品質等級: 200
• 化驗: ≥98%
• 形狀: powder
• 藥物控制: USDEA Schedule II; Home Office Schedule 2; stupéfiant (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)
• 顏色: white to off-white
• 溶解度: H₂O: 50 mg/mL, clear, colorless to yellow
• 起源: Novartis
• SMILES 字串: Cl.CCC(=O)C(CC(C)N(C)C)(c1ccccc1)c2ccccc2
• InChI: 1S/C21H27NO.ClH/c1-5-20(23)21(16-17(2)22(3)4,18-12-8-6-9-13-18)19-14-10-7-11-15-19;/h6-15,17H,5,16H2,1-4H3;1H
• InChI 密鑰: FJQXCDYVZAHXNS-UHFFFAOYSA-N
• 基因資訊: human ... OPRM1(4988)

说明

生化／生理作用

μ opioid receptor agonist that desensitizes both the μ opioid receptor and the δ opioid receptor on chronic exposure; narcotic analgesic, characterized by a gradual onset of action and prolonged, milder withdrawal; may also block L-type calcium channels independently of its effects on opioid receptors.

特點和優勢

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

安全信息

• 象形圖: GHS06
• 訊號詞: Danger
• 危險聲明: H300,H336
• 防範說明: P261 - P264 - P271 - P301 + P310 - P304 + P340 + P312 - P403 + P233
• 危險分類: Acute Tox. 2 Oral - STOT SE 3
• 標靶器官: Central nervous system
• 儲存類別代碼: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges