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MAK034

Sigma-Aldrich

辅酶A（CoA）检测试剂盒

sufficient for 100 colorimetric or fluorometric tests

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NACRES:
NA.84

用途

sufficient for 100 colorimetric or fluorometric tests

detection method

colorimetric
fluorometric

官能团

phospholipid

相关疾病

endocrinological disorders, diabetes; cancer

运输

wet ice

储存温度

−20°C

相关类别

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此商品
MAK039MAK086MAK332
Coenzyme A (CoA) Assay Kit sufficient for 100 colorimetric or fluorometric tests

Sigma-Aldrich

MAK034

辅酶A（CoA）检测试剂盒

Acetyl-Coenzyme A Assay Kit sufficient for 100 fluorometric tests

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MAK039

乙酰辅酶A检测试剂盒

Acetate Colorimetric Assay Kit sufficient for 100 colorimetric tests

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MAK086

乙酸盐检测试剂盒（比色法）

Pyruvate Assay Kit sufficient for 100 colorimetric or fluorometric tests

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MAK332

Pyruvate Assay Kit

detection method

colorimetric, fluorometric

detection method

fluorometric

detection method

colorimetric

detection method

colorimetric, fluorometric

shipped in

wet ice

shipped in

-

shipped in

-

shipped in

-

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

functional group

phospholipid

functional group

-

functional group

-

functional group

-

relevant disease(s)

endocrinological disorders, diabetes; cancer

relevant disease(s)

cancer; neurological disorders

relevant disease(s)

-

relevant disease(s)

gastrointestinal diseases; cancer

一般描述

辅酶A（CoA）是由半胱氨酸、泛酸和 ATP（三磷酸腺苷）合成的必需代谢辅助因子。CoA 在许多代谢途径中起重要作用，包括三羧酸循环，以及脂肪酸的合成和氧化。CoA 的主要功能之一是酰基的携带和转移。酰化衍生物，例如乙酰-CoA，是许多代谢反应中的关键中间体，特别是脂肪酸和碳水化合物代谢。在饥饿期间以及癌症、糖尿病和酗酒等条件下，CoA 水平可能会发生变化。

应用

辅酶 A（CoA）检测试剂盒已用于测量 CoA 水平。

特点和优势

兼容高通量处理系统。

适用性

适用于测量细胞和组织裂解液等各种生物样品中的辅酶 A（CoA）

原理

辅酶 A 检测试剂盒是一种测量各种生物样品中的 CoA 水平的简单方便的检测方法。CoA 浓度通过酶法测定，其产生与 CoA 浓度成比例的比色（570nm）/荧光测定（λex = 535 nm/λem = 587 nm）产物。该试剂盒的典型检测灵敏度为 0.1-10nmol CoA。

象形图

Health hazard
GHS08

警示用语：

Danger

危险声明

H319 - H334

危险分类

Eye Irrit. 2 - Resp. Sens. 1

储存分类代码

10 - Combustible liquids

WGK

WGK 3

闪点(F)

188.6 °F - closed cup

闪点(C)

87 °C - closed cup

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Molecular enzymology of carnitine transfer and transport.
Ramsay R R, et al.
Biochimica et Biophysica Acta (BBA)-Gene Structure and Expression, 1546(1), 21-43 (2001)
Nonalcoholic fatty liver disease and mitochondrial dysfunction.
Wei Y, et al.
World Journal of Gastroenterology, 14(2), 193-193 (2008)
Jing Tang et al.
The New phytologist, 228(6), 1880-1896 (2020-06-17)
The plant leaf surface is coated with a waterproof cuticle layer. Cuticle facing the stomatal pore surface needs to be sculpted to form outer cuticular ledge (OCL) after stomatal maturation for efficient gas exchange. Here, we characterized the roles of
Regulation of fatty acid biosynthesis in Escherichia coli.
Magnuson K, et al.
Microbiological Reviews, 57(3), 522-542 (1993)
Long-Chain Fatty Acyl-CoA Ligase FadD2 Mediates Intrinsic Pyrazinamide Resistance in Mycobacterium tuberculosis.
Rosen B C, et al.
Antimicrobial Agents and Chemotherapy, AAC-02130 (2016)
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