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About This Item
经验公式（希尔记法）:
C28H27ClF5NO
CAS Number:
分子量:
523.97
EC號碼:
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77
化驗
≥97% (HPLC)
形狀
powder
顏色
white
溶解度
DMSO: >20 mg/mL
H2O: insoluble
起源
Johnson & Johnson
儲存溫度
2-8°C
SMILES 字串
OC1(CCN(CCCC(c2ccc(F)cc2)c3ccc(F)cc3)CC1)c4ccc(Cl)c(c4)C(F)(F)F
InChI
1S/C28H27ClF5NO/c29-26-12-7-21(18-25(26)28(32,33)34)27(36)13-16-35(17-14-27)15-1-2-24(19-3-8-22(30)9-4-19)20-5-10-23(31)11-6-20/h3-12,18,24,36H,1-2,13-17H2
InChI 密鑰
MDLAAYDRRZXJIF-UHFFFAOYSA-N
應用
Penfluridol has been used as an antipsychotic agent:
- to study its antimetastatic effect on triple-negative breast cancer cells
- to study its effects on the growth of glioblastoma cell lines,
- to study its effects on the vascular endothelial growth factor (VEGF)-induced angiogenesis in human umbilical vein endothelial cells (HUVECs)
生化／生理作用
Penfluridol is studied in the treatment of schizophrenia, Tourette syndrome and acute psychosis. It also exhibits anticancer activity.
T-type Ca2+ channel blocker; antipsychotic
特點和優勢
This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
訊號詞
Danger
危險聲明
危險分類
Acute Tox. 3 Oral
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類（WGK）
WGK 3
個人防護裝備
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
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