Merck
  • P5864
All Photos(1)

P5864

Sigma-Aldrich

蛋白聚糖 来源于牛鼻中隔

chromatographically purified

All Photos(1)
MDL编号:
MFCD00212609
NACRES:
NA.61

生物来源

bovine nasal septum

质量水平

100

形式

powder

technique(s)

cell culture | stem cell: suitable

UniProt登记号

F1MDS0

储存温度

−20°C

Gene Information

bovine ... PRG4(280867)

Compare Similar Items

View Full Comparison

1 of 4

This Item
B8041A1960CC117
Sigma-Aldrich

Sigma-Aldrich

P5864

蛋白聚糖 来源于牛鼻中隔

Biglycan from bovine articular cartilage (essentially salt-free (from 0.2 μm filtered solution))

Sigma-Aldrich

B8041

Biglycan from bovine articular cartilage

Aggrecan from bovine articular cartilage lyophilized powder (from a sterile-filtered solution)

Sigma-Aldrich

A1960

聚集蛋白聚糖 来源于牛关节软骨

Chicken Extracellular Chondroitin Sulfate Proteoglycans

Sigma-Aldrich

CC117

鸡细胞外硫酸软骨素蛋白聚糖

biological source

bovine nasal septum

biological source

bovine articular cartilage

biological source

bovine articular cartilage

biological source

chicken

form

powder

form

essentially salt-free, lyophilized powder (from 0.2 μm filtered solution), (essentially salt-free (from 0.2 μm filtered solution))

form

lyophilized powder (from a sterile-filtered solution)

form

liquid

technique(s)

cell culture | stem cell: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

UniProt accession no.

F1MDS0

UniProt accession no.

P21809

UniProt accession no.

P13608

UniProt accession no.

P07898, Q90953, Q9W6E1

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

100, 300

一般描述

Proteoglycans are made up of a core protein to which glycosaminoglycan chains are linked covalently. They are present in many organs, and tissues and found abundantly in the vertebrate cartilage matrix. Proteoglycans are located in the extracellular and pericellular matrix of many cells.

应用

牛鼻中隔蛋白多糖含有86%的硫酸软骨素，已用于体外研究硫酸软骨素蛋白多糖的作用。已经证明它可以促进培养物中神经干细胞的存活。
Proteoglycan from bovine nasal septum has been used in the induction of arthritis in mice.

生化/生理作用

Proteoglycans are involved in tissue organization and promote cell growth and specialized tissue maturation. They act as biological filters and regulate collagen fibrillogenesis, skin tensile strength, and neurite growth. Proteoglycans are also involved in modulating growth-factor activities, affecting tumor cell growth and invasion, and promoting corneal transparency.

制备说明

通过改良的Antonopoulos程序，在DEAE-纤维素上使用7M尿素进行色谱纯化。

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

闪点(F)

Not applicable

闪点(C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service