Merck

P8920

Sigma-Aldrich

多聚-L-赖氨酸 溶液

0.1 % (w/v) in H2O

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别名:
2-(4-Cyanoanilino)-4,6-dichloropyrimidine, 4-[(4,6-Dichloro-2-pyrimidinyl)amino]benzonitrile
CAS号:
MDL编号:
eCl@ss:
32160406
NACRES:
NA.47

生物来源

synthetic

保质期

Expiry date on the label.

分子量

150,000-300,000

浓度

0.1 % (w/v) in H2O

颜色

colorless

application(s)

hematology
histology

储存温度

room temp

InChI

1S/C18H38N6O4/c19-10-4-1-7-13(22)16(25)23-14(8-2-5-11-20)17(26)24-15(18(27)28)9-3-6-12-21/h13-15H,1-12,19-22H2,(H,23,25)(H,24,26)(H,27,28)/t13-,14-,15-/m0/s1

InChI key

WBSCNDJQPKSPII-KKUMJFAQSA-N

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此商品
P4832P5899P6282
Poly-L-lysine solution 0.1 % (w/v) in H2O

Sigma-Aldrich

P8920

多聚-L-赖氨酸 溶液

Sigma-Aldrich

Sigma-Aldrich

P4832

多聚-L-赖氨酸 溶液

shelf life

Expiry date on the label.

shelf life

-

shelf life

-

shelf life

-

mol wt

150,000-300,000

mol wt

150,000-300,000

mol wt

≥300,000

mol wt

70,000-150,000

concentration

0.1 % (w/v) in H2O

concentration

0.01%

concentration

-

concentration

-

storage temp.

room temp

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−20°C

Quality Level

200

Quality Level

-

Quality Level

200

Quality Level

200

应用

聚-L-赖氨酸溶液已用于将内皮细胞横截面附着到UV交联的PET膜框架玻片上。聚-L-赖氨酸涂覆的玻片用于放置用于免疫组化检测的组织切片。
聚-L-赖氨酸聚合物可用于促进细胞对固体底物的粘附、与甲氨蝶呤结合以增加药物转运、胰岛微囊化、细胞微囊化技术、微阵列玻片涂层和染色体制剂。 较低分子量的聚-L-赖氨酸(30000-70000)在溶液中粘度较低,但分子量较高的聚赖氨酸在每个分子中提供更多的附着位点。

生化/生理作用

聚-L-赖氨酸是一种非特异性的细胞附着因子,通过增强细胞膜负离子与培养基表面的静电相互作用,促进细胞对固体基质的粘附。 当其吸附到细胞培养表面时,聚-L-赖氨酸的作用是增加可用于细胞结合的带正电荷位点的数量。 对于可降解聚-L-赖氨酸的细胞,应采用聚-D-赖氨酸作为附着因子。

组分

聚-L-赖氨酸是一种带正电荷的氨基酸聚合物,每个赖氨酸残基大约含有一个HBr。 氢溴酸盐使得聚-L-赖氨酸以晶体形式溶于水。 由于HBr会干扰氨基和羧基之间的氢键,或含有N或O基团之间的氢键,所以其产物中可能会发现少量的β结构产物。

制备说明

该产品以0.10%(w/v)水溶液形式提供的。用该溶液进行涂覆的玻片应当随后进行一步5分钟的孵育并在室温对其进行干燥。 涂覆的玻片在免收灰尘的保护下可稳定一年。

象形图

Exclamation markEnvironment

警示用语:

Warning

危险分类

Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1

储存分类代码

12 - Non Combustible Liquids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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