Merck

S6508

Sigma-Aldrich

正钒酸钠

≥90% (titration)

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别名:
Trisodium vanadate
线性分子式:
Na3VO4
CAS号:
分子量:
183.91
EC 号:
MDL编号:
PubChem化学物质编号:
NACRES:
NA.77

生物来源

synthetic (organic)

检测方案

≥90% (titration)

形式

crystalline powder

reaction suitability

reagent type: catalyst
core: vanadium

颜色

white to off-white

mp

850-866 °C (lit.)

溶解性

H2O: soluble

SMILES string

[Na+].[Na+].[Na+].[O-][V]([O-])([O-])=O

InChI

1S/3Na.4O.V/q3*+1;;3*-1;

InChI key

IHIXIJGXTJIKRB-UHFFFAOYSA-N

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450243204846567540
Sodium orthovanadate ≥90% (titration)

Sigma-Aldrich

S6508

正钒酸钠

Sodium orthovanadate 99.98% trace metals basis

Sigma-Aldrich

450243

正钒酸钠

Ammonium metavanadate 99.95% trace metals basis

Sigma-Aldrich

204846

偏钒酸铵

Sodium Orthovanadate A broad spectrum potent inhibitor of protein tyrosine phosphatases.

Sigma-Aldrich

567540

原钒酸钠

form

crystalline powder

form

solid

form

crystalline

form

solid

color

white to off-white

color

-

color

-

color

white to off-white

solubility

H2O: soluble

solubility

-

solubility

-

solubility

water: 10 mg/mL

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

100

biological source

synthetic (organic)

biological source

-

biological source

-

biological source

-

应用

正钒酸钠被用于制备胰岛素受体激酶脱磷酸化检测的终止液。26 它是用于开发利用表面固定抗体的Matrix ChIP的试剂之一。27

生化/生理作用

正钒酸钠可抑制辐射触发的p53介导的细胞凋亡激活。它减少了小鼠全身辐照引起的造血综合征、造血功能和延迟遗传毒性效应的不利影响。24 正钒酸盐与甲萘醌联合使用,可以防止脱落人胶质瘤细胞在抗癌药作用下发生迁移。25
抑制 ATP 酶、碱性磷酸酶和酪氨酸磷酸酶。在酸性 PH 值下形成的十钒酸盐可抑制肌醇基 1,4,5-三磷酸 (IP3)-诱导 Ca2+ 从内分泌细胞中的释放以及阻止 IP3 与其受体在脑组织中的结合。

特点和优势

《受体分类和信号转导》手册的 磷蛋白磷酸酶(酪氨酸) 页面有该化合物的介绍。想要浏览手册的其他页面, 请单击此处
该化合物是激酶磷酸酶生物学研究的特色产品。点击此处 ,查看更多激酶磷酸酶生物学精选产品。想要了解有关生物活性小分子在其他研究领域应用的更多信息,请访问 sigma.com/discover-bsm

象形图

Exclamation mark

警示用语:

Warning

危险分类

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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货号
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25G
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