SAB1407540

Sigma-Aldrich

Anti-KCNK10 antibody produced in mouse

purified immunoglobulin, buffered aqueous solution

别名:
TREK-2, K2p10.1, FLJ43399, TREK2
NACRES:
NA.41

质量水平

100

生物来源

mouse

抗体形式

purified immunoglobulin

antibody product type

primary antibodies

克隆

polyclonal

形式

buffered aqueous solution

分子量

antigen ~60.3 kDa

species reactivity

human

应用

western blot: 1 μg/mL

偶联物

unconjugated

NCBI登记号

UniProt登记号

运输

dry ice

储存温度

−20°C

Gene Information

human ... KCNK10(54207)

一般描述

The protein encoded by this gene belongs to the family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations, and is stimulated strongly by arachidonic acid and to a lesser degree by membrane stretching, intracellular acidification, and general anaesthetics. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene. (provided by RefSeq)

免疫原

KCNK10 (NP_612190.1, 1 a.a. ~ 543 a.a) full-length human protein.

Sequence
MKFPIETPRKQVNWDPKVAVPAAAPVCQPKSATNGQPPAPAPTPTPRLSISSRATVVARMEGTSQGGLQTVMKWKTVVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHALDADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVTIPAVIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYFAAVLSMIGDWLRVLSKKTKEEVGEIKAHAAEWKANVTAEFRETRRRLSVEIHDKLQRAATIRSMERRRLGLDQRAHSLDMLSPEKRSVFAALDTGRFKASSQESINNRPNNLRLKGPEQLNKHGQGASEDNIINKFGSTSRLTKRKNKDLKKTLPEDVQKIYKTFRNYSLDEEKKEEETEKMCNSDNSSTAMLTDCIQQHAELENGMIPTDTKDREPENNSLLEDRN

外形

Solution in phosphate buffered saline, pH 7.4

storage_class_code

13 - Non Combustible Solids

WGK Germany

WGK 1

闪点(F)

Not applicable

闪点(C)

Not applicable

分析证书

原产地证书 (CofO)

Zhaoyang Xiao et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(20), 7027-7042 (2014-05-16)
Neurotensin (NT) is a tridecapeptide distributed in the CNS, including the entorhinal cortex (EC), a structure that is crucial for learning and memory and undergoes the earliest pathological alterations in Alzheimer's disease (AD). Whereas NT has been implicated in modulating...

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