Merck

SAB2702233

Sigma-Aldrich

Monoclonal Anti-Dengue virus Envelope protein antibody produced in mouse

clone GT643, affinity isolated antibody

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NACRES:
NA.41

生物来源

mouse

质量水平

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

GT643, monoclonal

形式

buffered aqueous solution

分子量

51-60kDa

种属反应性

Dengue virus

浓度

1mg/mL

技术

flow cytometry: suitable
immunofluorescence: 1:100-1:2,000
western blot: 1:500-1:3,000

同位素/亚型

IgG2b

运输

wet ice

储存温度

−20°C

靶向翻译后修饰

unmodified

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1 of 4

此商品
MAB8701MAB8703MAB8702
conjugate

unconjugated

conjugate

-

conjugate

-

conjugate

-

biological source

mouse

biological source

mouse

biological source

mouse

biological source

mouse

clone

GT643, monoclonal

clone

15F3-1, monoclonal

clone

5D4-11, monoclonal

clone

3H5-1, monoclonal

antibody form

affinity isolated antibody

antibody form

purified antibody

antibody form

purified antibody

antibody form

purified immunoglobulin

technique(s)

flow cytometry: suitable, western blot: 1:500-1:3,000, immunofluorescence: 1:100-1:2,000

technique(s)

immunofluorescence: suitable

technique(s)

immunofluorescence: suitable

technique(s)

immunofluorescence: suitable, inhibition assay: suitable (hemagglutination)

一般描述

Dengue virus is an arthropod borne flavivirus. Dengue virus (DENV) is a human pathogen, known to cause one of the major illness, dengue fever (DF) in humans. DENV belongs to the Flaviviridae family. The virus attaches and enters the host cell with the help of a major envelope protein glycoprotein, E. The dengue envelope protein sequence consists of two putative glycosaminoglycan-binding motifs at the carboxy terminus.

免疫原

Recombinant protein encompassing a sequence within the center region of Dengue virus Envelope protein.

应用

Suggested starting dilutions are as follows: ICC/IF: 1:100-1:2000, WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

其他说明

Purification: Affinity purified by Protein G

外形

Phosphate-buffered saline, no preservative added.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存分类代码

12 - Non Combustible Liquids

WGK

nwg

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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索取COA

Type-and subcomplex-specific neutralizing antibodies against domain III of dengue virus type 2 envelope protein recognize adjacent epitopes.
Sukupolvi-Petty S, et al.
Journal of Virology, 81(23), 12816-12826 (2007)
Ankit Kumar et al.
Asian journal of transfusion science, 16(1), 67-72 (2022-10-07)
The study objective was evaluation of amotosalen and ultraviolet A (UVA) illumination-based inactivation of dengue virus (DENV) in blood platelets. Whole blood was collected from healthy donors and platelet concentrates were prepared at a tertiary care hospital in Gurugram, India.
Dengue virus infectivity depends on envelope protein binding to target cell heparan sulfate.
Chen Y, et al.
Nature Medicine, 3(8), 866-866 (1997)
A ligand-binding pocket in the dengue virus envelope glycoprotein.
Modis Y, et al.
Proceedings of the National Academy of Sciences of the USA, 100(12), 6986-6991 (2003)

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