Merck

SAB4502580

Sigma-Aldrich

Anti-Retinoic Acid Receptor α antibody produced in rabbit

affinity isolated antibody

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别名:
NR1B1, Nuclear receptor subfamily 1 group B member 1, RAR-α, RARA, Retinoic acid receptor α
MDL编号:
NACRES:
NA.41

生物来源

rabbit

质量水平

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

形式

buffered aqueous solution

分子量

antigen 50 kDa

种属反应性

human, mouse, rat

浓度

~1 mg/mL

技术

ELISA: 1:10000
western blot: 1:500-1:1000

NCBI登记号

UniProt登记号

运输

wet ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... RARA(5914)

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此商品
SAB1411972SAB1412190WH0005914M1
biological source

rabbit

biological source

mouse

biological source

mouse

biological source

mouse

antibody form

affinity isolated antibody

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

mol wt

antigen 50 kDa

mol wt

antigen 37.84 kDa

mol wt

antigen 37.84 kDa

mol wt

-

clone

polyclonal

clone

1C10, monoclonal

clone

4B3, monoclonal

clone

2C9-1F8, monoclonal

一般描述

Anti-Retinoic Acid Receptor α Antibody detects endogenous levels of total Retinoic Acid Receptor α protein.
Retinoic acid receptor α (RARα) is a nuclear receptor for retinoic acid and is expressed in the retina. It belongs to the nuclear steroid/thyroid hormone receptor superfamily. The gene encoding it is localized on human chromosome 17q21.

免疫原

The antiserum was produced against synthesized peptide derived from human Retinoic Acid Receptor alpha.

Immunogen Range: 46-95

生化/生理作用

Retinoic acid receptor α (RARα) is a ligand-dependent transcriptional modulator of genes that has a role in differentiation, cellular development and apoptosis. It has a role in germ-cell development in testis. The protein may be associated with acute promyelocytic leukemia.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存分类代码

10 - Combustible liquids

WGK

nwg

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Enhanced expression of retinoic acid receptor alpha (RARA) induces epithelial-to-mesenchymal transition and disruption of mammary acinar structures.
Doi A
Molecular Oncology, 9(2), 355-364 (2015)
Activity of retinoic acid receptor-alpha is directly regulated at its protein kinase A sites in response to follicle-stimulating hormone signaling.
Santos NC and Kim KH
Endocrinology, 151(5), 2361-2372 (2010)
NLS-RARa promotes proliferation and inhibits differentiation in HL-60 cells.
Hu XX
International Journal of Medical Sciences, 11(3), 247-254 (2014)
The retinoic acid receptor alpha (RARA) gene is not associated with myopia, hypermetropia, and ocular biometric measures.
Veerappan S
Molecular Vision, 15, 1390-1397 (2009)

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