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SAB4503014

抗-p53 (乙酰赖氨酸³¹⁷)，C末端兔抗

affinity isolated antibody

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别名:

TP53, 抗原NY-CO-13, 磷酸化蛋白p53, 细胞肿瘤抗原p53, 肿瘤抑制因子p53

NACRES:

NA.41

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此商品	SAB4503020	SAB4503018	SAB4502616
Sigma-Aldrich SAB4503014 抗-p53 (乙酰赖氨酸³¹⁷)，C末端兔抗	Sigma-Aldrich SAB4503020 Anti-p53 (Acetyl-Lys³⁸⁶), C-Terminal antibody produced in rabbit	Sigma-Aldrich SAB4503018 Anti-p53 (Acetyl-Lys³⁷⁹), C-Terminal antibody produced in rabbit	Sigma-Aldrich SAB4502616 Anti-NF-κB p65 (Acetyl-Lys³¹⁰) antibody produced in rabbit
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody
clone polyclonal	clone polyclonal	clone polyclonal	clone polyclonal
form buffered aqueous solution	form buffered aqueous solution	form buffered aqueous solution	form buffered aqueous solution
mol wt antigen 43 kDa	mol wt antigen 43 kDa	mol wt antigen 43 kDa	mol wt antigen 60 kDa

一般描述

p53（乙酰基-Lys317）抗体可用于检测总p53（乙酰基-Lys317）的内源性水平。

免疫原

针对从人p53 Lys317的乙酰化位点周围衍生的合成肽产生抗血清。

免疫原范围：283-332

应用

成功使用该抗体的应用以及相关的同行评审论文如下所示。
蛋白质免疫印迹分析（1篇论文）

特点和优势

您可完全放心的评估我们的抗体。如果抗体在您的应用中没有发挥效果，我们将给予您完全的赔偿或更换抗体。了解更多。

外形

兔IgG，溶于磷酸盐缓冲盐水（不含Mg2+和Ca2+），pH7.4,150mM NaCl，0.02％叠氮化钠和50％甘油中。

免责声明

除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

储存分类代码

10 - Combustible liquids

WGK

nwg

闪点(F)

Not applicable

闪点(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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示例

T1503

货号

25G

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其它示例：

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

请输入1.000309185)

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Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

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如果您查询到的批号为 TO09019TO 等，请输入去除前两位字母的批号：09019TO。
如果您查询到的批号含有填充代码（例如05427ES-021），请输入去除填充代码-021的批号：05427ES。
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索取COA

Neuregulin-1 attenuates stress-induced vascular senescence.

Hadis Shakeri et al.

Cardiovascular research, 114(7), 1041-1051 (2018-03-13)

Cardiovascular ageing is a key determinant of life expectancy. Cellular senescence, a state of irreversible cell cycle arrest, is an important contributor to ageing due to the accumulation of damaged cells. Targeting cellular senescence could prevent age-related cardiovascular diseases. In

Defective autophagy in vascular smooth muscle cells accelerates senescence and promotes neointima formation and atherogenesis.

Mandy Oj Grootaert et al.

Autophagy, 11(11), 2014-2032 (2015-09-24)

Autophagy is triggered in vascular smooth muscle cells (VSMCs) of diseased arterial vessels. However, the role of VSMC autophagy in cardiovascular disease is poorly understood. Therefore, we investigated the effect of defective autophagy on VSMC survival and phenotype and its

SIRT3 deficiency exacerbates p53/Parkin‑mediated mitophagy inhibition and promotes mitochondrial dysfunction: Implication for aged hearts.

Yan Li et al.

International journal of molecular medicine, 41(6), 3517-3526 (2018-03-14)

Mitochondrial dynamics have critical roles in aging, and their impairment represents a prominent risk factor for myocardial dysfunction. Mitochondrial deacetylase sirtuin (SIRT)3 contributes greatly to the prevention of redox stress and cell aging. The present study explored the role of SIRT3

商品

p53: DNA Damage Response and Cancer

p53 regulates gene expression, cell cycle control and functions as a tumor suppressor. Inactivation of p53 is closely tied to cancer development.

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抗-p53 (乙酰赖氨酸317)，C末端 兔抗

affinity isolated antibody

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