SAB4503015

Anti-p53 antibody produced in rabbit

affinity isolated antibody

• 别名: Antigen NY-CO-13, Cellular tumor antigen p53, Phosphoprotein p53, TP53, tumor protein p53
• NACRES: NA.41

属性

• 生物来源: rabbit
• 偶联物: unconjugated
• 抗体形式: affinity isolated antibody
• antibody product type: primary antibodies
• 克隆: polyclonal
• 形式: buffered aqueous solution
• 分子量: antigen 43 kDa
• species reactivity: mouse, human, rat
• 浓度: ~1 mg/mL
• technique(s): ELISA: 1:10000; immunofluorescence: 1:100-1:500; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI登记号: P04637
• UniProt登记号: P04637
• 运输: wet ice
• 储存温度: −20°C
• Gene Information: human ... TP53(7157)

说明

一般描述

Anti-p53 Antibody detects endogenous levels of total p53 protein.

TP53 gene is mapped to human chromosome 17p13.1.

免疫原

The antiserum was produced against synthesized peptide derived from human p53.

Immunogen Range: 283-332

生化/生理作用

TP53 gene is involved in the regulation of cell cycle, senescence and apoptosis upon oncogene activation, stress and DNA damage. Therefore, the gene has anti-tumor activity initiation and prevents tumor progression. Mutation in TP53 is known to be the major cause of almost half of all human malignancy. Breast cancer is one such condition in which, the disease development is severe due to mutation in TP53 gene.

特点和优势

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外形

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全信息

• 储存分类代码: 10 - Combustible liquids
• WGK: nwg
• 闪点(F): Not applicable
• 闪点(C): Not applicable