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SAB4503018

Anti-p53 (Acetyl-Lys³⁷⁹), C-Terminal antibody produced in rabbit

affinity isolated antibody

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别名:

Antigen NY-CO-13, Cellular tumor antigen p53, Phosphoprotein p53, TP53, Tumor suppressor p53

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此商品	SAB4503020	SAB4503014	SAB4502616
Sigma-Aldrich SAB4503018 Anti-p53 (Acetyl-Lys³⁷⁹), C-Terminal antibody produced in rabbit	Sigma-Aldrich SAB4503020 Anti-p53 (Acetyl-Lys³⁸⁶), C-Terminal antibody produced in rabbit	Sigma-Aldrich SAB4503014 抗-p53 (乙酰赖氨酸³¹⁷)，C末端兔抗	Sigma-Aldrich SAB4502616 Anti-NF-κB p65 (Acetyl-Lys³¹⁰) antibody produced in rabbit
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody
clone polyclonal	clone polyclonal	clone polyclonal	clone polyclonal
form buffered aqueous solution	form buffered aqueous solution	form buffered aqueous solution	form buffered aqueous solution
mol wt antigen 43 kDa	mol wt antigen 43 kDa	mol wt antigen 43 kDa	mol wt antigen 60 kDa

一般描述

Anti-p53 (Acetyl-Lys379) Antibody detects endogenous levels of total p53 (Acetyl-Lys379) protein.

免疫原

The antiserum was produced against synthesized peptide derived from human p53 around the acetylated site of Lys379.

Immunogen Range: 344-393

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存分类代码

10 - Combustible liquids

WGK

nwg

闪点(F)

Not applicable

闪点(C)

Not applicable

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Endoplasmic Reticulum (ER) Stress Induces Sirtuin 1 (SIRT1) Expression via the PI3K-Akt-GSK3β Signaling Pathway and Promotes Hepatocellular Injury.

Tomoaki Koga et al.

The Journal of biological chemistry, 290(51), 30366-30374 (2015-10-27)

Sirtuin 1 (SIRT1), an NAD(+)-dependent histone deacetylase, plays crucial roles in various biological processes including longevity, stress response, and cell survival. Endoplasmic reticulum (ER) stress is caused by dysfunction of ER homeostasis and exacerbates various diseases including diabetes, fatty liver

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p53: DNA Damage Response and Cancer

p53 regulates gene expression, cell cycle control and functions as a tumor suppressor. Inactivation of p53 is closely tied to cancer development.

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Anti-p53 (Acetyl-Lys379), C-Terminal antibody produced in rabbit

affinity isolated antibody

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属性

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偶联物

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antibody product type

克隆

形式

分子量

species reactivity

浓度

technique(s)

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