Merck

SAB5500022

Sigma-Aldrich

Anti-E-Cadherin antibody, Rabbit monoclonal

recombinant, expressed in proprietary host, clone SP64, affinity isolated antibody

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NACRES:
NA.41

生物来源

rabbit

质量水平

重组

expressed in proprietary host

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

SP64, monoclonal

种属反应性

human (tested)

技术

immunoblotting: 1:25
immunohistochemistry: 1:100

同位素/亚型

IgG

UniProt登记号

运输

wet ice

储存温度

2-8°C

靶向翻译后修饰

unmodified

基因信息

human ... CDH1(999)

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此商品
SAB5700789SAB5700696SAB4500001
抗-E-钙粘蛋白抗体(兔)

SAB5700789

抗-E-钙粘蛋白抗体(兔)

biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

rabbit

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

clone

SP64, monoclonal

clone

polyclonal

clone

polyclonal

clone

polyclonal

species reactivity

human (tested)

species reactivity

mouse, human, rat

species reactivity

rat, human, mouse

species reactivity

human, rat, mouse

Gene Information

human ... CDH1(999)

Gene Information

human ... CDH1(999)

Gene Information

human ... CDH1(999)

Gene Information

human ... CDH1(999)

一般描述

E-cadherin (uvomorulin, cell-CAM120/80) is a calcium dependent cell adhesion molecule expressed predominately in epithelial tissues. It plays an important role in the growth and development of cells via the mechanisms of control of tissue architecture and the maintenance of tissue integrity. Numerous studies have demonstrated that reduction and/or loss of E-cadherin expression in carcinomas correlates positively with the potential of these tumors for invasion and metastasis.

免疫原

Recombinant protein encoding aa 600-707 of human cadherin-E.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存分类代码

10 - Combustible liquids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Cheng Zhang et al.
Oncology letters, 13(4), 2059-2070 (2017-04-30)
Human bone marrow stromal cells (hBMSCs) may contribute to the growth of tyrosine kinase inhibitor (TKI)-resistant chronic myelogenous leukemia (CML). However, there are certain differences in biology between CML and Philadelphia-positive acute lymphoblastic leukemia (Ph+ ALL). Little is known about
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Chemotherapy is one of the methods to treat patients with non-small cell lung cancer (NSCLC) developing resistance to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs), such as gefitinib. Previous studies revealed that the sensitivity to chemotherapy may depend

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