Merck

SAB5500057

Sigma-Aldrich

Anti-CD3 antibody, Rabbit monoclonal

clone SP162, recombinant, expressed in proprietary host, affinity isolated antibody

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别名:
Anti-CD3epsilon, Anti-IMD18, Anti-T3E, Anti-TCRE
NACRES:
NA.41

生物来源

rabbit

质量水平

重组

expressed in proprietary host

偶联物

unconjugated

抗体形式

affinity isolated antibody

antibody product type

primary antibodies

克隆

SP162, monoclonal

species reactivity

human (tested)

species reactivity (predicted by homology)

rat, chicken, rabbit, mouse, pig, bovine, dog

technique(s)

flow cytometry: 1:150
immunoblotting: 1:150
immunohistochemistry: 1:150

同位素/亚型

IgG

UniProt登记号

运输

wet ice

储存温度

2-8°C

target post-translational modification

unmodified

Gene Information

human ... CD3E(916)

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此商品
SAB5500058SAB5500059SAB5500037
recombinant

expressed in proprietary host

recombinant

expressed in proprietary host

recombinant

expressed in proprietary host

recombinant

expressed in proprietary host

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody form

tissue culture supernatant

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

clone

SP162, monoclonal

clone

SP7, monoclonal

clone

SP164, monoclonal

clone

SP182, monoclonal

species reactivity

human (tested)

species reactivity

human (tested)

species reactivity

human (tested)

species reactivity

human (tested)

一般描述

CD3E (CD3e molecule) gene is mapped to human chromosome 11q23.3. This gene encodes fora subunit of T-cell regulator (TCR) protein complex. It possesses IgG (immunoglobulin G)-like extracelluar domain at the N-terminal, a transmembrane domain, a peptide bridge and an immunoreceptor tyrosine-based activation motif (ITAM) towards the cytoplasm. The protein also contains basic residue-rich sequence (BRS).
This antibody reacts with the intracytoplasmic portion of the CD3 antigen expressed by T cells. It stains human T cells in both the cortex and medulla of the thymus and in peripheral lymphoid tissues. This antibody is suitable for staining normal and neoplastic T cells in formalin-fixed, paraffin-embedded tissues.

免疫原

Synthetic peptide corresponding to internal region of the epsilon chain of human CD3 protein.

应用

Anti-CD3 antibody, Rabbit monoclonal has been used in immunohistochemistry.

生化/生理作用

CD3E (CD3e molecule) gene is associated with actin cytoskeletal rearrangement, through activation of a number of signaling pathways. CD3E is essential for membrane binding of T-cell regulator (TCR) protein complex.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存分类代码

10 - Combustible liquids

WGK

WGK 2

闪点(F)

Not applicable

闪点(C)

Not applicable


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