Merck

SAB5700558

Sigma-Aldrich

Anti-Phospho-TP53-S15 antibody produced in rabbit

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别名:
BCC7, BMFS5, LFS1, P53, TP53, TRP53, p53

生物来源

rabbit

质量水平

抗体形式

affinity isolated antibody

antibody product type

primary antibodies

克隆

polyclonal

形式

buffered aqueous solution

分子量

43

species reactivity

human

浓度

1.06mg/ml

technique(s)

western blot: 1:500-1:2000

UniProt登记号

运输

wet ice

储存温度

−20°C

target post-translational modification

phosphorylation (pSer15)

Gene Information

human ... TP53(7157)

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此商品
SAB5700560SAB5700440SAB5700364
antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

rabbit

clone

polyclonal

clone

polyclonal

clone

polyclonal

clone

polyclonal

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

technique(s)

western blot: 1:500-1:2000

technique(s)

western blot: 1:500-1:2000

technique(s)

immunohistochemistry: 1:50-1:100, immunoprecipitation (IP): 1:50-1:100, western blot: 1:500-1:2000

technique(s)

immunoprecipitation (IP): 1:50-1:100, western blot: 1:1000-1:2000

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一般描述

This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277).

免疫原

A phospho specific peptide corresponding to residues surrounding S15 of human p53.

外形

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

储存及稳定性

Store at -20℃. Avoid freeze / thaw cycles.

储存分类代码

12 - Non Combustible Liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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