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Merck

SCP0030

Sigma-Aldrich

[Gly22]-Amyloid β 1-42 Arctic human

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About This Item

经验公式(希尔记法):
C200H307N55O58S1
分子量:
4441.98
分類程式碼代碼:
12352209
NACRES:
NA.32

化驗

≥95% (HPLC)

形狀

lyophilized

成份

Peptide Content, ≥75%

儲存條件

protect from light

UniProt登錄號

儲存溫度

−20°C

基因資訊

human ... APP(351)

Amino Acid Sequence

Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Gly-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala

一般說明

β-Amyloid 1-42 is one of the major constituents of the neurofibrillary tangles and plaques characteristic of the Alzheimer brain. The Arctic mutation E22G causes early onset of Alzheimer′s compared to wild type and promotes protofibril formation and neurotoxicity.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Qiujian Yu et al.
Biological research, 51(1), 35-35 (2018-09-21)
The previous studies have demonstrated the reduction of thiamine diphosphate is specific to Alzheimer's disease (AD) and causal factor of brain glucose hypometabolism, which is considered as a neurodegenerative index of AD and closely correlates with the degree of cognitive

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