MISSION^® siRNA产品系列

Predesigned siRNA

Extensive collection of human, mouse and rat siRNA. Multiple sequences are available for every gene, with rankings to indicate performance.

• Scale: 10, 25, 50, and 250 nmol
• Purification: Desalt or HPLC
• Sequence Length: 21 bases
• Modifications: Not available for this item
• Quality Control: Individual strands are analyzed by mass spectrometry. Depending on manufacturing site, PAGE may be used to assess siRNA duplexes. siRNA quantity is systematically validated by UV absorbance at 260 nm.
• Format: Supplied dry

Custom siRNA

Custom siRNA sequences with a wide range of modifications, purifications and quantities to tailor your unique sequence.

• Scale: 10, 25, 50, and 250 nmol
• Purification: Desalt or HPLC
• Sequence Lengths: 19 - 27 bases
• Modifications: Comprehensive offering of modifications and dyes (2'-O-Methyl, Amine, Cyanine dyes, 6-FAM, Biotin, Phosphate, Thiol, Abasic, Phosphorothioate linkages, 2'-Fluoro).
• Quality Control: Individual strands are analyzed by mass spectrometry. Depending on manufacturing site, PAGE may be used to assess siRNA duplexes. siRNA quantity is systematically validated by UV absorbance at 260 nm.
• For additional purifications, sequence length or modifications,
  email sirnarequest@sial.com
• Custom siRNA sequence design available for a variety of species,
  Learn more

Fast siRNA

Expedite your siRNA order! Orders are prioritized in the production process with a turn-around-time of only 3 days.

• FAST siRNA is delivered in solution at concentrations of 50 µM (2 OD) or 100 µM (5 OD).
• US orders must be received by 11 AM CST. European orders must be received by 11 AM CET.
• Easy to use Fast siRNA ordering tool.

iScale Oligos™ - siRNA

siRNA provided in larger quantities for in vivo, high throughput or diagnostic projects.

• Amount: 1 – 10 mg, 50 mg – 1 g
• Purification: Desalt, RPC (cartridge purified), HPLC and In vivo quality
• Sequence Length: 19 - 45 bases
• Comprehensive offering of modifications including dyes, amines, biotin, linkers, etc.
• Quality Control: Individual strands are analyzed by mass spectrometry. Depending on manufacturing site, PAGE may be used to assess siRNA duplexes. siRNA quantity is systematically validated by UV absorbance at 260 nm.
• In vivo option includes HPLC-purification to >/= 90%, desalt, filtration and endotoxin testing.
• To inquire for availability of additional quantities, modifications or purifications, email sirnarequest@sial.com

siRNA Controls

Universal Negative Controls

• Two distinct siRNA control sequences designed for use in Human, Mouse, or Rat cells.
• Validated with Agilent 40K human gene arrays to ensure no significant nonspecific gene interactions.
• Functionally validated to show no immune response via qRT PCR.

Positive Control siRNA.

• Validated human and rat positive controls to simplify transfection optimization.

RNA Oligos

• Scale: 0.05, 0.2, 1.0 µmol
• Purification: Desalt, HPLC and PAGE
• Sequence Length: 7 - 45 bases
• Modification options available
• Quality Control: 100% Mass Spectrometry
• Format: Supplied dry
• Learn more about RNA Oligos

MISSION^® siRNA Transfection Reagent

• Superior gene silencing in a wide variety of eukaryotic cell types
• For use with siRNA, esiRNA, miRNA mimics and Synthetic miRNA inhibitors