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About This Item
经验公式（希尔记法）:
C18H17N3O4S · HCl
CAS Number:
分子量:
407.87
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.25
品質等級
化驗
≥98% (HPLC)
形狀
powder
儲存條件
desiccated
顏色
pink to purple
溶解度
DMSO: ≥15 mg/mL
起源
Abbott
儲存溫度
2-8°C
SMILES 字串
Cl.COc1ccc(cc1)S(=O)(=O)Nc2cccnc2Nc3ccc(O)cc3
InChI
1S/C18H17N3O4S.ClH/c1-25-15-8-10-16(11-9-15)26(23,24)21-17-3-2-12-19-18(17)20-13-4-6-14(22)7-5-13;/h2-12,21-22H,1H3,(H,19,20);1H
InChI 密鑰
KWQWWUXRGIIBAS-UHFFFAOYSA-N
生化／生理作用
ABT-751 is an orally bioavailable vascular disrupting agent (VDA) with a broad spectrum of antitumor activity. It binds to the colchicine binding site on β-tubulin and inhibits polymerization of microtubules.
ABT-751, a sulfonamide antimitotic agent, is under clinical trials to treat patients with various malignancies including refractory hematologic malignancies, non-small cell lung cancer (NSCLC), and colon cancer.
Orally bioavailable vascular disrupting agent (VDA) that binds to the colchicine binding site on β-tubulin and inhibits polymerization of microtubules; broad spectrum of antitumor activity.
特點和優勢
This compound was developed by Abbott. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
訊號詞
Warning
危險分類
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
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