Merck
所有图片(1)

文件

SML0517

Sigma-Aldrich

Amlexanox

≥98% (HPLC)

所有图片(1)
别名:
2-Amino-7-(1-methylethyl)-5-oxo-5H-[1]Benzopyrano[2,3-b]pyridine-3-carboxylic acid, AA 673, Amoxanox, CHX 3673
Empirical Formula (Hill Notation):
C16H14N2O4
CAS号:
68302-57-8
分子量:
298.29
MDL编号:
MFCD00864790
PubChem化学物质编号:
329825526
NACRES:
NA.77

质量水平

100

检测方案

≥98% (HPLC)

形式

powder

颜色

white to beige

溶解性

DMSO: 10 mg/mL at warmed, clear

运输

wet ice

储存温度

−20°C

SMILES string

CC(C)c1ccc2Oc3nc(N)c(cc3C(=O)c2c1)C(O)=O

InChI

1S/C16H14N2O4/c1-7(2)8-3-4-12-9(5-8)13(19)10-6-11(16(20)21)14(17)18-15(10)22-12/h3-7H,1-2H3,(H2,17,18)(H,20,21)

InChI key

SGRYPYWGNKJSDL-UHFFFAOYSA-N

Gene Information

human ... PDE4A(5141) , PDE4B(5142) , PDE4C(5143) , PDE4D(5144)

正在寻找类似产品? Visit 产品对比指南

比较类似商品

查看完整比较结果

Show Differences

1 of 4

此商品
PZ0179H3661SML1423
Amlexanox ≥98% (HPLC)

Sigma-Aldrich

SML0517

Amlexanox

Valdecoxib ≥98% (HPLC)

Sigma-Aldrich

PZ0179

伐地昔布

4′-Hydroxydiclofenac ≥98% (HPLC)

Sigma-Aldrich

H3661

4′-羟基双氯芬酸

Pranoprofen ≥98% (HPLC)

Sigma-Aldrich

SML1423

普拉洛芬

form

powder

form

powder

form

-

form

powder

color

white to beige

color

white to off-white

color

-

color

white to beige

solubility

DMSO: 10 mg/mL at warmed, clear

solubility

DMSO: >25 mg/mL

solubility

-

solubility

DMSO: 20 mg/mL, clear

shipped in

wet ice

shipped in

-

shipped in

-

shipped in

-

storage temp.

−20°C

storage temp.

room temp

storage temp.

−20°C

storage temp.

2-8°C

一般描述

Amlexanox is an anti-allergic drug with anti-inflammatory properties.

生化/生理作用

Amlexanox elevates the amount of nonsense-containing mRNAs in treated cells and helps to generate full-length proteins effectively.
Amlexanox is an anti-allergy and anti-asthma drug that blocks histamine and leukotriene release from leukocytes and mast cells. Amlexanox has also been shown to inhibit cahaperone activity of Hsp90, and S100A13, which is involved in transport of proteins devoid of signal peptide sequences.

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H302

危险分类

Acute Tox. 4 Oral

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(F)

Not applicable

闪点(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

在网站页面上，产品编号会附带包装尺寸/数量一起显示（例如：T1503-25G）。请确保 在“产品编号”字段中仅输入产品编号 (示例 T1503).

示例

T1503
货号
-
25G
包装规格/数量

其它示例：

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

请输入1.000309185)

遇到问题？欢迎随时联系我们技术服务 寻求帮助

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich 产品

  • 如果您查询到的批号为 TO09019TO 等，请输入去除前两位字母的批号：09019TO。

  • 如果您查询到的批号含有填充代码（例如05427ES-021），请输入去除填充代码-021的批号：05427ES。

  • 如果您查询到的批号含有填充代码（例如 STBB0728K9），请输入去除填充代码K9的批号：STBB0728。

未找到您寻找的产品？

部分情况下，可能未在线提供COA。如果搜索不到COA，可在线索取。

索取COA

其他客户在看

Slide 1 of 7

1 of 7

Bovine Serum Albumin heat shock fraction, pH 5.2, ≥96%

Sigma-Aldrich

A8022

牛血清白蛋白 来源于牛血清

Sigma-Aldrich

Sigma-Aldrich

E1378

七叶皂苷

Tofacitinib citrate ≥98% (HPLC)

Sigma-Aldrich

PZ0017

Tofacitinib（托法替尼）柠檬酸盐

Acridine Orange hydrochloride hydrate ≥98% (HPLC)

Sigma-Aldrich

318337

吖啶橙 盐酸盐 水合物

Influenza Hemagglutinin (HA) Peptide ≥97% (HPLC)

Sigma-Aldrich

I2149

流行性感冒血凝素 (HA) 肽

Nickel on silica/alumina extent of labeling: ~65 wt. % loading, powder

Sigma-Aldrich

208779

二氧化硅/氧化铝负载镍

Wortmannin from Penicillium funiculosum, ≥98% (HPLC and TLC)

Sigma-Aldrich

W1628

渥曼青霉素

Sandhya G Rani et al.
Biochemistry, 49(11), 2585-2592 (2010-02-25)
S100A13 and acidic fibroblast growth factor (FGF1) are involved in a wide array of important biological processes, such as angiogenesis, cell differentiation, neurogenesis, and tumor growth. Generally, the biological function of FGF1 is to recognize a specific tyrosine kinase on
Shannon M Reilly et al.
Nature medicine, 19(3), 313-321 (2013-02-12)
Emerging evidence suggests that inflammation provides a link between obesity and insulin resistance. The noncanonical IκB kinases IKK-ɛ and TANK-binding kinase 1 (TBK1) are induced in liver and fat by NF-κB activation upon high-fat diet feeding and in turn initiate
R W Barrons
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 58(1), 41-50 (2001-02-24)
The clinical features, etiology, and treatment of recurrent aphthous ulcers (RAU) are discussed. Aphthous ulcers are among the most common oral lesions in the general population, with a frequency of up to 25% and three-month recurrence rates as high as
F Tarantini et al.
The Journal of biological chemistry, 276(7), 5147-5151 (2000-11-23)
Interleukin (IL)1alpha mediates proinflammatory events through its extracellular interaction with the IL1 type I receptor. However, IL1alpha does not contain a conventional signal peptide sequence that provides access to the endoplasmic reticulum-Golgi apparatus for secretion. Thus, we have studied the
M Sugiura et al.
Contact dermatitis, 38(2), 65-67 (1998-03-20)
A 23-year-old woman developed allergic rhinitis in 1993. Her doctor prescribed for her Solfa (amlexanox 25 mg) and Lysozymen 90 (lysozyme chloride 90 mg) tablets. She took the tablets occasionally, whenever she developed allergic rhinitis. She noticed a macular erythema
查看所有相关文献

相关内容

Discover Bioactive Small Molecules for Immunology Research

We offer agonists, antagonists, modulators and other bioactive small molecules for immune system signaling target identification and validation, as well as a variety of antibiotics, antivirals, and antifungals.

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门