T3067

Monoclonal Anti-TRAIL antibody produced in mouse

clone 75411, purified immunoglobulin, lyophilized powder

• Synonym(s): Anti-TNFSF10, Anti-TNF-Related Apoptosis-Inducing Ligand
• MDL编号: MFCD01868284
• NACRES: NA.41

Properties

• 质量水平: 100
• 生物来源: mouse
• 偶联物: unconjugated
• 抗体形式: purified immunoglobulin
• antibody product type: primary antibodies
• 克隆: 75411, monoclonal
• 形式: lyophilized powder
• species reactivity: human
• technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 8-25 μg/mL using human brain (occipital cortex) tissue sections; neutralization: 28 ng/mL using L929 mouse fibroblast cell line
• 同位素/亚型: IgG1
• UniProt登记号: P50591
• 储存温度: −20°C
• Gene Information: human ... TNFSF10(8743)

Description

一般描述

Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) is a member of the tumor necrosis factor (TNF) cytokine family. This ligand is a type II transmembrane protein that contains a short cytoplasmic N-terminal domain and a long C-terminal extracellular receptor-binding domain. TRAIL is highly expressed in immune system cells. The TRAIL gene is located on the human chromosome at 3q26.31.

免疫原

purified, NSO-derived, recombinant human TRAIL extracellular domain.

应用

Monoclonal Anti-TRAIL antibody produced in mouse has been used in fluorescence-activated cell sorting (FACS).

生化/生理作用

Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) binds to TRAIL 1 & 2 receptors and induces apoptosis. This ligand is involved in the homeostasis of T-cells and natural killer (NK) cells. TRAIL also aids in the T-cell-mediated killing of virus-infected cells and oncogenic transformed cells.

外形

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• 储存分类代码: 11 - Combustible Solids
• WGK: WGK 3
• 闪点(F): Not applicable
• 闪点(C): Not applicable