Merck

WH0004893M1

Sigma-Aldrich

Monoclonal Anti-NRAS antibody produced in mouse

clone 2A3, purified immunoglobulin, buffered aqueous solution

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别名:
Anti-NRAS1, Anti-Nras, Anti-neuroblastoma RAS viral (v-ras) oncogene homolog
MDL编号:

生物来源

mouse

质量水平

偶联物

unconjugated

抗体形式

purified immunoglobulin

抗体产品类型

primary antibodies

克隆

2A3, monoclonal

形式

buffered aqueous solution

种属反应性

human

技术

indirect ELISA: suitable
western blot: 1-5 μg/mL

同位素/亚型

IgGκ

GenBank登记号

UniProt登记号

运输

dry ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... NRAS(4893)

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1 of 4

此商品
SAB4200778SAB3501039SAB4200779
species reactivity

human

species reactivity

human

species reactivity

human, mouse, rat

species reactivity

human

Gene Information

human ... NRAS(4893)

Gene Information

human ... NRAS(4893)

Gene Information

human ... NRAS(4893)

Gene Information

human ... NRAS(4893)

clone

2A3, monoclonal

clone

polyclonal

clone

polyclonal

clone

polyclonal

conjugate

unconjugated

conjugate

-

conjugate

unconjugated

conjugate

-

biological source

mouse

biological source

rabbit

biological source

rabbit

biological source

rabbit

一般描述

This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated to a GTP-bound form by a GTPase activating protein and inactivated to a GDP-bound form by a guanine nucleotide-exchange factor. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). (provided by RefSeq)

免疫原

NRAS (AAH05219, 90 a.a. ~ 189 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
FADINLYREQIKRVKDSDDVPMVLVGNKCDLPTRTVDTKQAHELAKSYGIPFIETSAKTRQGVEDAFYTLVREIRQYRMKKLNSSDDGTQGCMGLPCVVM

外形

Solution in phosphate buffered saline, pH 7.4

法律信息

GenBank is a registered trademark of United States Department of Health and Human Services

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存分类代码

10 - Combustible liquids

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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