WH0006556M1

Monoclonal Anti-SLC11A1 antibody produced in mouse

clone 2G2, purified immunoglobulin, buffered aqueous solution

• Synonym(s): Anti-LSH, Anti-NRAMP, Anti-NRAMP1, Anti-solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
• NACRES: NA.41

Properties

• 生物来源: mouse
• 质量水平: 100
• 偶联物: unconjugated
• 抗体形式: purified immunoglobulin
• antibody product type: primary antibodies
• 克隆: 2G2, monoclonal
• 形式: buffered aqueous solution
• species reactivity: human
• technique(s): indirect ELISA: suitable; western blot: 1-5 μg/mL
• 同位素/亚型: IgG1κ
• GenBank® accession no.: NM_000578
• UniProt登记号: P49279
• 运输: dry ice
• 储存温度: −20°C
• Gene Information: human ... SLC11A1(6556)

Description

一般描述

This gene is a member of the solute carrier family 11 (proton-coupled divalent metal ion transporters) family and encodes a multi-pass membrane protein. The protein functions as a divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Mutations in this gene have been associated with susceptibility to infectious diseases such as tuberculosis and leprosy, and inflammatory diseases such as rheumatoid arthritis and Crohn disease. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined. (provided by RefSeq)

免疫原

SLC11A1 (NP_000569.2, 308 a.a. ~ 350 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
QAFYQKTNQAAFNICANSSLHDYAKIFPMNNATVAVDIYQGGV

外形

Solution in phosphate buffered saline, pH 7.4

法律信息

GenBank is a registered trademark of United States Department of Health and Human Services

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• 储存分类代码: 10 - Combustible liquids
• 闪点(F): Not applicable
• 闪点(C): Not applicable
• 个人防护装备: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)