所有图片(1)

X1126

Sigma-Aldrich

甲苯噻嗪

≥99%

别名:
2-(2,6-二甲基苯氨基)-5,6-二氢-4H-噻嗪
Empirical Formula (Hill Notation):
C12H16N2S
CAS号:
分子量:
220.33
EC 号:
MDL编号:
PubChem化学物质编号:
NACRES:
NA.77

质量水平

200

测定

≥99%

储存温度

−20°C

SMILES string

Cc1cccc(C)c1NC2=NCCCS2

InChI

1S/C12H16N2S/c1-9-5-3-6-10(2)11(9)14-12-13-7-4-8-15-12/h3,5-6H,4,7-8H2,1-2H3,(H,13,14)

InChI key

BPICBUSOMSTKRF-UHFFFAOYSA-N

一般描述

甲苯噻嗪可溶于甲醇 (50 mg/mL),得到澄清、无色溶液。也可溶于稀盐酸和氯仿。甲苯噻嗪几乎不溶于水和碱溶液。

应用

甲苯噻嗪已用于实验动物的麻醉。

生化/生理作用

与氯胺酮一起使用时,甲苯噻嗪被认为是实验动物中一种强效和安全的麻醉剂。已知其可升高肝脏释放葡萄糖,从而加重高血糖症。
α 2 -肾上腺素受体激动剂、镇静剂、肌肉松弛剂。

其他说明

斯克里普斯代谢组学和质谱技术中心独立生成的串联质谱数据可在PDFX1126.pdf 中查看或下载。斯克里普斯代谢物组学和质谱技术中心的METLIN代谢物数据库中有测试代谢物。要了解更多信息,请访问sigma.com/metlin。

象形图

Skull and crossbones

警示用语:

Danger

危险声明

预防措施声明

Hazard Classifications

Acute Tox. 3 Oral

Storage Class Code

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK Germany

WGK 3

闪点(F)

Not applicable

闪点(C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

分析证书

原产地证书 (CofO)

Effect of xylazine on plasma glucose, glucagon and insulin concentrations in sheep
Brockman, RP
Research in Veterinary Science, 30(3), 383-384 (1981)
Lactobacillus casei addition to a repletion diet-induced early normalisation of cytokine profils during a pneumococcal infection in malnourished mice
Salva S, et al.
Food and agricultural immunology, 19(3), 195-211 (2008)
Naomi Van Gassen et al.
European journal of immunology, 45(5), 1482-1493 (2015-02-04)
Pancreas injury by partial duct ligation (PDL) activates a healing response, encompassing β-cell neogenesis and proliferation. Macrophages (MΦs) were recently shown to promote β-cell proliferation after PDL, but they remain poorly characterized. We assessed myeloid cell diversity and the factors...
Imaging of rat optic nerve axons in vivo
Koch JC, et al.
Nature Protocols, 6(12), 1887-1887 (2011)
Hannah T Nickles et al.
American journal of physiology. Lung cellular and molecular physiology, 307(1), L27-L37 (2014-05-13)
The pathogenesis of ventilator-induced lung injury has predominantly been attributed to overdistension or mechanical opening and collapse of alveoli, whereas mechanical strain on the airways is rarely taken into consideration. Here, we hypothesized that mechanical ventilation may cause significant airway...

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