1001502

USP

乙酰丙嗪 马来酸盐

United States Pharmacopeia (USP) Reference Standard

别名:
乙酰丙嗪 马来酸盐, 2-乙酰基-10-(3-二甲基氨基丙基)吩噻嗪 马来酸盐
Empirical Formula (Hill Notation):
C19H22N2OS · C4H4O4
CAS号:
分子量:
442.53
MDL编号:
PubChem化学物质编号:
NACRES:
NA.24

等级

pharmaceutical primary standard

形式

neat

manufacturer/tradename

USP

特色行业

Pharmaceutical (small molecule)

格式

neat

SMILES string

OC(=O)\C=C/C(O)=O.CN(C)CCCN1c2ccccc2Sc3ccc(cc13)C(C)=O

InChI

1S/C19H22N2OS.C4H4O4/c1-14(22)15-9-10-19-17(13-15)21(12-6-11-20(2)3)16-7-4-5-8-18(16)23-19;5-3(6)1-2-4(7)8/h4-5,7-10,13H,6,11-12H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1-

InChI key

FQRHOOHLUYHMGG-BTJKTKAUSA-N

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一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

乙酰丙嗪是一种吩噻嗪类抗精神病药,仅用作兽药(马、狗和猫)。该化合物是抗精神病药物氯丙嗪(#C8138)的类似物。该药物被认为可以阻断大脑中的多巴胺受体。最近发现该化合物抑制 ABCG2 转运蛋白,该蛋白在肿瘤中的过表达与耐药性有关。

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

象形图

Skull and crossbones

警示用语:

Danger

危险声明

预防措施声明

hazcat

Acute Tox. 3 Oral - STOT SE 3

靶器官

Central nervous system

storage_class_code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK Germany

WGK 1

闪点(F)

Not applicable

闪点(C)

Not applicable

分析证书

原产地证书 (CofO)

Elizabeth A Nunamaker et al.
Journal of the American Association for Laboratory Animal Science : JAALAS, 53(5), 494-501 (2014-09-26)
The goal of the current study was to compare the efficacy, adverse effects, and plasma buprenorphine concentrations of sustained-release buprenorphine (SRB) and buprenorphine after subcutaneous administration in dogs undergoing ovariohysterectomy. In a prospective, randomized, blinded design, 20 healthy adult female...
Samer M Jaber et al.
Journal of the American Association for Laboratory Animal Science : JAALAS, 53(6), 684-691 (2015-02-05)
Extending a surgical plane of anesthesia in mice by using injectable anesthetics typically is accomplished by repeat-bolus dosing. We compared the safety and efficacy of redosing protocols administered either during an anesthetic surgical plane (maintaining a continuous surgical plane, CSP)...
Cathryn M Kolka et al.
Metabolism: clinical and experimental, 64(2), 330-337 (2014-12-04)
Insulin injected directly into skeletal muscle diffuses rapidly through the interstitial space to cause glucose uptake, but this is blocked in insulin resistance. As glucotoxicity is associated with endothelial dysfunction, the observed hyperglycemia in diet-induced obese dogs may inhibit insulin...
Amadeu Gavaldà et al.
Pulmonary pharmacology & therapeutics, 28(2), 114-121 (2014-06-15)
This study characterised the in vitro and in vivo profiles of two novel long-acting muscarinic antagonists, aclidinium bromide and glycopyrronium bromide, using tiotropium bromide and ipratropium bromide as comparators. All four antagonists had high affinity for the five muscarinic receptor sub-types (M1-M5);...
Jinmei Wei et al.
Journal of the science of food and agriculture, 95(3), 598-606 (2014-06-21)
The use of xenobiotic compounds in animal husbandry has given rise to consumer anxieties regarding residual risk and food safety. Thus, animal tissues have become main samples for residue analysis and food safety for sedatives. In this study, a rapid...

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