所有图片(1)

1491004

USP

土霉素

United States Pharmacopeia (USP) Reference Standard

别名:
土霉素 二水合物
Empirical Formula (Hill Notation):
C22H24N2O9 · 2H2O
CAS号:
分子量:
496.46
EC 号:
MDL编号:
PubChem化学物质编号:
NACRES:
NA.24

等级

pharmaceutical primary standard

形式

neat

manufacturer/tradename

USP

特色行业

Pharmaceutical (small molecule)

格式

neat

SMILES string

O.[H][C@@]12[C@@H](O)[C@@]3([H])C(C(=O)c4c(O)cccc4[C@@]3(C)O)=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@H]2N(C)C

InChI

1S/C22H24N2O9.H2O/c1-21(32)7-5-4-6-8(25)9(7)15(26)10-12(21)17(28)13-14(24(2)3)16(27)11(20(23)31)19(30)22(13,33)18(10)29;/h4-6,12-14,17,25,27-29,32-33H,1-3H3,(H2,23,31);1H2/t12-,13-,14+,17+,21-,22+;/m1./s1

InChI key

IBZHEBHGZFICKS-IFLJXUKPSA-N

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一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

Antibiotic produced by Streptomyces rimosus.
Mode of Action: Inhibits protein synthesis (elongation) by preventing binding of aminoacyl-tRNA to the 30S subunit.
Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.
Mode of Resistance: Active efflux, ribosome protection, tetracycline inactivation.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

象形图

Health hazardEnvironment

警示用语:

Warning

危险声明

Hazard Classifications

Aquatic Chronic 2 - Repr. 2

Storage Class Code

11 - Combustible Solids

WGK Germany

WGK 3

闪点(F)

Not applicable

闪点(C)

Not applicable

分析证书

原产地证书 (CofO)

更多文件

Support vector regression for determination of component of compound oxytetracycline powder on near-infrared spectroscopy.
Tingting Zou et al.
Analytical biochemistry, 355(1), 1-7 (2006-05-26)
Hrvoje Petković et al.
Microbiology and molecular biology reviews : MMBR, 70(3), 704-728 (2006-09-09)
From a genetic standpoint, Streptomyces rimosus is arguably the best-characterized industrial streptomycete as the producer of oxytetracycline and other tetracycline antibiotics. Although resistance to these antibiotics has reduced their clinical use in recent years, tetracyclines have an increasing role in...
Extralabel use of oxytetracycline.
T Martin-Jimenez et al.
Journal of the American Veterinary Medical Association, 211(1), 42-44 (1997-07-01)
Lauren B Pickens et al.
The Journal of biological chemistry, 285(36), 27509-27515 (2010-06-05)
Oxytetracycline (OTC) is a broad-spectrum antibiotic that acts by inhibiting protein synthesis in bacteria. It is an important member of the bacterial aromatic polyketide family, which is a structurally diverse class of natural products. OTC is synthesized by a type...
Alireza Khadem et al.
The British journal of nutrition, 112(7), 1110-1118 (2014-09-03)
The non-antibiotic anti-inflammatory theory of antimicrobial growth promoters (AGP) predicts that alternatives can be selected by simple in vitro tests. In vitro, the known AGP oxytetracycline (OTC) and a Macleaya cordata extract (MCE) had an anti-inflammatory effect with a half-maximal...

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