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Maria Francesca Piacentini et al.
International journal of sports physiology and performance, 11(6), 824-830 (2015-12-15)
Monitoring mood state is a useful tool for avoiding nonfunctional overreaching. Brain-derived neurotrophic factor (BDNF) is implicated in stress-related mood disorders. To investigate the impact of intensified training-induced mood disturbance on plasma BDNF concentrations at rest and in response to...
Steven Keiles et al.
Pancreas, 33(3), 221-227 (2006-09-28)
Chronic pancreatitis is a progressive inflammatory disorder leading to irreversible exocrine and/or endocrine impairment. It is well documented that mutations in the cationic trypsinogen (PRSS1) gene can cause hereditary pancreatitis. Mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) and...
S O'Neill et al.
The British journal of surgery, 100(13), 1689-1700 (2013-11-15)
Vascular clamping reduces blood loss during liver resection but leads to ischaemia-reperfusion injury. Ischaemic preconditioning (IP) may reduce this. This study aimed to evaluate IP in liver resection under clamping. This was a systematic review and meta-analysis of randomized clinical...
Rami Kantor et al.
Journal of the International AIDS Society, 17, 19262-19262 (2014-11-22)
Antiretroviral resistance leads to treatment failure and resistance transmission. Resistance data in western Kenya are limited. Collection of non-plasma analytes may provide additional resistance information. We assessed HIV diversity using the REGA tool, transmitted resistance by the WHO mutation list...
C D Petraki et al.
Prostate cancer and prostatic diseases, 6(3), 223-227 (2003-09-13)
Human kallikreins 6, 10 and 13 (hK6, hK10 and hK13) are expressed by many normal, mainly glandular tissues, including prostatic epithelium. Some kallikreins may function as tumor suppressors or are downregulated during cancer progression. The aim of this study was...
Paulo Castro-Chaves et al.
European journal of pharmacology, 544(1-3), 91-96 (2006-07-18)
We analyzed the influence of endothelin-1 and endocardial endothelium on the myocardial effects of angiotensin-II. Angiotensin-II (10(-9)-10(-5) M) was tested in rabbit right papillary muscles in absence (Protocol-A) or presence of PD-145065 (10(-7) M; Protocol-B), BQ-123 (10(-7) M; Protocol-C) or...
Nancy R Keller et al.
Circulation, 110(10), 1191-1196 (2004-09-01)
Norepinephrine (NE) is a primary neurotransmitter of central autonomic regulation and sympathetic nerve conduction, and the norepinephrine transporter (NET) is crucial in limiting catecholaminergic signaling. NET is sensitive to antidepressants, cocaine, and amphetamine. NET blockade often is associated with cardiovascular...
Janet D Klein et al.
Journal of the American Society of Nephrology : JASN, 15(5), 1161-1167 (2004-04-22)
The UT-B urea transporter is the major urea transporter in red blood cells and kidney descending vasa recta. Humans and mice that lack UT-B have a mild urine-concentrating defect. Whether deletion of UT-B altered the expression of other transporter proteins...
Akito Chinen et al.
Molecular biology and evolution, 22(4), 1001-1010 (2005-01-14)
We previously reported that zebrafish have four tandemly duplicated green (RH2) opsin genes (RH2-1, RH2-2, RH2-3, and RH2-4). Absorption spectra vary widely among the four photopigments reconstituted with 11-cis retinal, with their peak absorption spectra (lambda(max)) being 467, 476, 488...
Tom Edward Nightingale et al.
PloS one, 10(5), e0126086-e0126086 (2015-05-09)
To assess the validity of two accelerometer devices, at two different anatomical locations, for the prediction of physical activity energy expenditure (PAEE) in manual wheelchair users (MWUs). Seventeen MWUs (36 ± 10 yrs, 72 ± 11 kg) completed ten activities;...
Masahiro Yoshida et al.
Journal of bacteriology, 186(20), 6855-6863 (2004-10-07)
We found the occurrence of thermophilic reversible gamma-resorcylate decarboxylase (gamma-RDC) in the cell extract of a bacterium isolated from natural water, Rhizobium sp. strain MTP-10005, and purified the enzyme to homogeneity. The molecular mass of the enzyme was determined to...
Ping Jin et al.
Zhonghua fu chan ke za zhi, 46(5), 329-332 (2011-07-08)
To investigate the effect of Interleukin (IL)-18, IL-12 and tumor necrosis factor-α (TNF-α) in hepatic injury in intrahepatic cholestasis of pregnancy (ICP). Sixty-two cases of ICP patients (ICP group), 30 cases of normal pregnant women (control group) and 30 cases...
Daniela Accorsi-Mendonça et al.
Journal of neurophysiology, 121(5), 1822-1830 (2019-03-21)
Sustained hypoxia (SH) activates chemoreceptors to produce cardiovascular and respiratory responses to bring the arterial partial pressure of O2 back to the physiological range. We evaluated the effect of SH (fraction of inspired O2 = 0.10, 24 h) on glutamatergic synaptic transmission...
Elodie Dessalces et al.
JAMA ophthalmology, 131(10), 1314-1323 (2013-08-10)
Retinitis punctata albescens (RPA) is an autosomal recessive form of retinitis pigmentosa characterized by white dotlike deposits in the fundus, in most cases caused by mutations in RLBP1. To study disease progression and visual function in RPA. We performed clinical...
Emanuel R Tenorio et al.
Journal of vascular surgery, 71(6), 1982-1993 (2019-10-16)
The objective of this study was to analyze the utility of cone beam computed tomography (CBCT) for technical assessment of standard and complex endovascular aneurysm repair (EVAR). Data of consecutive patients who underwent standard or complex EVAR in 2016 and...
Baoguo Ren et al.
Journal of the National Cancer Institute, 99(11), 868-880 (2007-06-07)
Integrins are the major adhesive molecules in mammalian cells. Each integrin subtype plays a unique role in cell differentiation and embryo development. However, integrin involvement in carcinogenesis has not been well defined. We identified mutations in integrin alpha7 by sequencing...
Karen M Edmond et al.
Lancet (London, England), 385(9975), 1315-1323 (2014-12-17)
Results of randomised controlled trials of newborn (age 1-3 days) vitamin A supplementation have been inconclusive. The WHO is coordinating three large randomised trials in Ghana, India, and Tanzania (Neovita trials). We present the findings of the Neovita trial in...
Philipp Zanger et al.
The Lancet. Infectious diseases, 13(11), 946-954 (2013-09-10)
Travellers' diarrhoea causes substantial acute and long-term morbidity. Chemoprophylaxis with fluoroquinolones or rifaximin is effective in prevention of diarrhoea in individuals travelling to Latin America and Africa. Little evidence is available to support the protective effect of antimicrobial drugs in...
R Garside et al.
Health technology assessment (Winchester, England), 11(45), iii-iiv (2007-11-15)
To assess the clinical and cost-effectiveness of adjuvant carmustine wafers (BCNU-W) and also of adjuvant and concomitant temozolomide (TMZ), compared with surgery with radiotherapy. Electronic databases were searched up to August 2005. Included trials were critically appraised for key elements...