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Nan Zhang et al.
Diabetes, 53(4), 963-970 (2004-03-30)
Successful islet transplantation depends on the infusion of sufficiently large quantities of islets, of which only approximately 30% become stably engrafted. Rapid and adequate revascularization of transplanted islets is important for islet survival and function. Delayed and insufficient revascularization can
Neonatal hypoxia-ischemia differentially upregulates MAGUKs and associated proteins in PSD-93-deficient mouse brain
Jiang, X., et al
Stroke, 34, 2958-2963 (2003)
Wahn Soo Choi et al.
Molecular and cellular biology, 24(16), 6980-6992 (2004-07-30)
Both phospholipase D1 (PLD1) and PLD2 regulate degranulation when RBL-2H3 cells are stimulated via the immunoglobulin E receptor, Fc epsilon RI. However, the activation mechanism for PLD2 is unclear. As reported here, PLD2 but not PLD1 is phosphorylated through the
Murat Digicaylioglu et al.
Proceedings of the National Academy of Sciences of the United States of America, 101(26), 9855-9860 (2004-06-24)
Erythropoietin (EPO) and insulin-like growth factor I (IGF-I) are cytokines that inhibit neuronal apoptosis. However, their maximal antiapoptotic effect, even at high concentrations, is observed only when neurons are pretreated for several hours before insult. Here we show that simultaneous
Jennifer Altomonte et al.
American journal of physiology. Endocrinology and metabolism, 285(4), E718-E728 (2003-06-05)
Excessive hepatic glucose production is a contributing factor to fasting hyperglycemia in diabetes. Insulin suppresses hepatic glucose production by inhibiting the expression of two gluconeogenic enzymes, phosphoenolpyruvate carboxykinase (PEPCK) and glucose-6-phosphatase (G-6-Pase). The forkhead transcription factor Foxo1 has been implicated
Sarah M Senf et al.
American journal of physiology. Cell physiology, 300(6), C1490-C1501 (2011-03-11)
The Forkhead Box O (FOXO) transcription factors regulate diverse cellular processes, and in skeletal muscle are both necessary and sufficient for muscle atrophy. Although the regulation of FOXO by Akt is well evidenced in skeletal muscle, the current study demonstrates
The expression of p63 is associated with the differential stage in nasopharyngeal carcinoma and EBV infection
Guo, Can, et al
Journal of Translational Medicine, 4, 23-23 (2006)
Blocking of the alpha interferon-induced Jak-Stat signaling pathway by Japanese encephalitis virus infection
Lin, R. J., et al
Journal of virology, 78, 9285-9294 (2004)
Jinbiao Chen et al.
The international journal of biochemistry & cell biology, 43(6), 905-912 (2011-03-23)
A three amino acid sequence, Ser/Thr-Pro-Ser/Thr, was recently identified and characterized as a novel nuclear localization signal (Chuderland et al., 2008). The immediate-early gene product, early growth response-1 is a three zinc finger containing transcription factor implicated in a wide
Kevin Petrie et al.
The Journal of biological chemistry, 278(18), 16059-16072 (2003-02-19)
Histone deacetylases (HDACs) perform an important function in transcriptional regulation by modifying the core histones of the nucleosome. We have now fully characterized a new member of the Class II HDAC family, HDAC9. The enzyme contains a conserved deacetylase domain
Enhanced protein recovery and reproducibility from pull-down assays and immunoprecipitations using spin columns.
A Brymora et al.
Analytical biochemistry, 295(1), 119-122 (2001-07-31)
E-Y Huang et al.
Cell death & disease, 3, e251-e251 (2012-01-13)
Galectin-1 is a lectin recognized by galactoside-containing glycoproteins, and is involved in cancer progression and metastasis. The role of galectin-1 in radiosensitivity has not previously been investigated. Therefore, this study tests whether galectin-1 is involved in the radiosensitivity mediated by
Activation of FAK is necessary for the osteogenic differentiation of human mesenchymal stem cells on laminin-5.
Roman M Salasznyk,Robert F Klees,Adele Boskey,George E Plopper
Journal of Cellular Biochemistry null
James LR, Le C, Scholey JW
American Journal of Physiology. Endocrinology and Metabolism null
Bile acid regulation of C/EBPbeta, CREB, and c-Jun function, via the extracellular signal-regulated kinase and c-Jun NH2-terminal kinase pathways, modulates the apoptotic response of hepatocytes
Qiao, L., et al
Molecular and cellular biology, 23, 3052-3066 (2003)
Liang-Nian Song et al.
Molecular endocrinology (Baltimore, Md.), 18(1), 70-85 (2003-11-01)
Mifepristone is a potent antagonist of steroid hormone receptors such as glucocorticoid and progesterone receptors. We investigated the potential for mifepristone to act as an antiandrogen and compared it with partial androgen receptor (AR) agonists and antagonists, in particular bicalutamide.
Niall J Lennon et al.
The Journal of biological chemistry, 278(50), 50466-50473 (2003-09-25)
Mutations in the dysferlin gene cause limb girdle muscular dystrophy type 2B and Miyoshi myopathy. We report here the results of expression profile analyses and in vitro investigations that point to an interaction between dysferlin and the Ca2+ and lipid-binding
Roman M Salasznyk et al.
Experimental cell research, 313(1), 22-37 (2006-11-04)
The intracellular signaling events controlling human mesenchymal stem cells (hMSC) differentiation into osteoblasts are not entirely understood. We recently demonstrated that contact with extracellular matrix (ECM) proteins is sufficient to induce osteogenic differentiation of hMSC through an ERK-dependent pathway. We
Wanxia He et al.
Journal of virology, 77(19), 10566-10574 (2003-09-13)
Addition of human papillomavirus (HPV) E7 CDK2/cyclin A or CDK2/cyclin E, purified from either insect cells or bacteria, dramatically upregulates histone H1 kinase activity. Activation is substrate specific, with a smaller effect noted for retinoblastoma protein (Rb). The CDK2 stimulatory
Hypercholesterolemia-induced Abeta accumulation in rabbit brain is associated with alteration in IGF-1 signaling.
Sharma, Sunita, et al.
Neurobiology of Disease, 32, 426-432 (2008)
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