Miguel Álvaro-Benito et al.
Journal of immunology (Baltimore, Md. : 1950), 194(2), 803-816 (2014-12-17)
During the adaptive immune response, MHCII proteins display antigenic peptides on the cell surface of APCs for CD4(+) T cell surveillance. HLA-DM, a nonclassical MHCII protein, acts as a peptide exchange catalyst for MHCII, editing the peptide repertoire. Although they