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[A WHO concept- patient blood management].

Oliver M Theusinger

Praxis, 103(21), 1257-1262 (2014-10-12)

Blood transfusions are in general considered as lifesaving. Current data and evidence show, that blood transfusions are associated with increased morbidity and mortality, and this apparently dose-dependent. Basic research and results from randomized controlled trials show a causal relationship between

Characterization of a periplasmic nitrate reductase in complex with its biosynthetic chaperone.

Jennifer M Dow et al.

The FEBS journal, 281(1), 246-260 (2013-12-10)

Escherichia coli is a Gram-negative bacterium that can use nitrate during anaerobic respiration. The catalytic subunit of the periplasmic nitrate reductase NapA contains two types of redox cofactor and is exported across the cytoplasmic membrane by the twin-arginine protein transport

Effects of magnesium, chromium, iron and zinc from food supplements on selected aquatic organisms.

Jasna Bosnir et al.

Collegium antropologicum, 37(3), 965-971 (2013-12-07)

The aim of this study was to determine the effect of uncontrolled environmental disposal of food supplements containing magnesium (Mg), chromium (Cr), iron (Fe) and zinc (Zn) on selected aquatic organisms including freshwater algae Scenedesmus subspicatus and Raphidocelis subcapitata, water

Genetic hemoglobin disorders rather than iron deficiency are a major predictor of hemoglobin concentration in women of reproductive age in rural prey Veng, Cambodia.

Crystal D Karakochuk et al.

The Journal of nutrition, 145(1), 134-142 (2014-12-21)

Anemia is common in Cambodian women. Potential causes include micronutrient deficiencies, genetic hemoglobin disorders, inflammation, and disease. We aimed to investigate factors associated with anemia (low hemoglobin concentration) in rural Cambodian women (18-45 y) and to investigate the relations between

A systematic analysis reveals an essential role for high-affinity iron uptake system, haemolysin and CFEM domain-containing protein in iron homoeostasis and virulence in Candida glabrata.

Vivek Kumar Srivastava et al.

The Biochemical journal, 463(1), 103-114 (2014-07-06)

Iron is an essential nutrient for all living organisms and human pathogens employ a battery of factors to scavenge iron from the high-affinity iron-binding host proteins. In the present study, we have elucidated, via a candidate gene approach, major iron

[Not Available].

MMW Fortschritte der Medizin, 155(11), 25-25 (2013-08-02)

Metal solubilization from powdered printed circuit boards by microbial consortium from bauxite and pyrite ores.

N N Adhapure et al.

Prikladnaia biokhimiia i mikrobiologiia, 49(3), 279-284 (2013-07-26)

With the current rapid developments in technology, there is an increasing accumulation of outdated electronic equipment. The primary reason for this increase is the low rate of recycling due to the complex nature of such waste. Bioleaching offers a promising

Hemoglobin binding and catalytic heme extraction by IsdB near iron transporter domains.

Catherine F M Bowden et al.

Biochemistry, 53(14), 2286-2294 (2014-03-22)

The Isd (iron-regulated surface determinant) system is a multiprotein transporter that allows bacterium Staphylococcus aureus to take up iron from hemoglobin (Hb) during human infection. In this system, IsdB is a cell wall-anchored surface protein that contains two near iron

The role of intravenous iron for the treatment of restless legs syndrome.

Michael Auerbach

American journal of hematology, 89(10), 1016-1016 (2014-08-05)

Iron increases APP translation and amyloid-beta production in the retina.

Lucie Y Guo et al.

Experimental eye research, 129, 31-37 (2014-12-03)

Age-related macular degeneration (AMD) is the most common cause of blindness among older adults in developed countries, and retinal iron accumulation may exacerbate the disease. Iron can upregulate the production of amyloid precursor protein (APP). Since amyloid-β (Aβ), a byproduct

Removal of benzotriazole by heterogeneous photoelectro-Fenton like process using ZnFe2O4 nanoparticles as catalyst.

Junfeng Wu et al.

Journal of environmental sciences (China), 25(4), 801-807 (2013-08-09)

ZnFe2O4 nanoparticles (ZFNPs) were developed as catalyst for the degradation of benzotriazole (BTA) by heterogeneous photoelectro-Fenton (PE-Fenton) like process. ZFNPs were prepared by a co-precipitation process and then characterized with transmission electron microscopy (TEM), X-ray fluorescence (XRF), X-ray diffraction (XRD)

Intestinal inflammation modulates expression of the iron-regulating hormone hepcidin depending on erythropoietic activity and the commensal microbiota.

Nanda Kumar N Shanmugam et al.

Journal of immunology (Baltimore, Md. : 1950), 193(3), 1398-1407 (2014-06-29)

States of chronic inflammation such as inflammatory bowel disease are often associated with dysregulated iron metabolism and the consequent development of an anemia that is caused by maldistribution of iron. Abnormally elevated expression of the hormone hepcidin, the central regulator

Hepatic iron in African Americans who underwent liver biopsy.

James C Barton et al.

The American journal of the medical sciences, 349(1), 50-55 (2015-01-07)

Primary iron overload in African Americans has been reported predominantly from autopsy studies. We characterized hepatic iron phenotypes in 83 African Americans who underwent liver biopsy during the interval 1990 to 1995. We tabulated pathology report form data, iron grades

[The frequency of anemia in children with newly diagnosed Crohn's disease in children].

Tomasz Pytrus et al.

Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 34(203), 263-268 (2013-07-31)

The aim of the study was to analyze the occurrence of anemia in children with newly diagnosed Crohn's disease and 3 months after the initiation of treatment depending on location and activity of the disease. 36 children aged from 2

A comparative study of the iron status of patients with oesophageal adenocarcinoma to determine suitability for a clinical trial of iron chelation therapy.

S J Ford et al.

Annals of the Royal College of Surgeons of England, 96(4), 275-278 (2014-05-02)

The incidence of oesophageal adenocarcinoma (OAC) is rising dramatically and overall survival remains extremely poor. Iron has been shown to potentiate tumourigenesis in OAC, and iron chelation therapy demonstrates promise in vivo as an adjunct to neoadjuvant and palliative chemotherapy.

[Cutting-edge of medicine; iron metabolism--recent findings].

Hideo Harigae

Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 102(10), 2699-2704 (2014-01-10)

The iron-based phosphate binder PA21 has potent phosphate binding capacity and minimal iron release across a physiological pH range in vitro.

Maria Wilhelm et al.

Clinical nephrology, 81(4), 251-258 (2014-03-25)

Hyperphosphatemia in advanced chronic kidney disease (CKD) necessitates the use of phosphate binders. This in vitro study assessed phosphate binding and Fe release properties of the novel iron-based phosphate binder PA21. Phosphate adsorption and Fe release were assessed under conditions

Iron homeostasis in breast cancer.

Oriana Marques et al.

Cancer letters, 347(1), 1-14 (2014-02-04)

Iron is an essential element and a critical component of molecules involved in energy production, cell cycle and intermediate metabolism. However, the same characteristic chemistry that makes it so biologically versatile may lead to iron-associated toxicity as a consequence of

Efficacy of sonazoid (perflubutane) for contrast-enhanced ultrasound in the differentiation of focal breast lesions: phase 3 multicenter clinical trial.

Yukio Miyamoto et al.

AJR. American journal of roentgenology, 202(4), W400-W407 (2014-03-26)

The objective of our study was to compare the efficacy of contrast-enhanced ultrasound (CEUS) using the ultrasound contrast agent Sonazoid (perflubutane) with unenhanced ultrasound and supplementary contrast-enhanced MRI in the differential diagnosis (benign vs malignant) of focal breast lesions. The

Origins of R2* orientation dependence in gray and white matter.

David A Rudko et al.

Proceedings of the National Academy of Sciences of the United States of America, 111(1), E159-E167 (2014-01-01)

Estimates of the apparent transverse relaxation rate (R2*) can be used to quantify important properties of biological tissue. Surprisingly, the mechanism of R2* dependence on tissue orientation is not well understood. The primary goal of this paper was to characterize

Utilization of host iron sources by Corynebacterium diphtheriae: multiple hemoglobin-binding proteins are essential for the use of iron from the hemoglobin-haptoglobin complex.

Courtni E Allen et al.

Journal of bacteriology, 197(3), 553-562 (2014-11-19)

The use of hemin iron by Corynebacterium diphtheriae requires the DtxR- and iron-regulated ABC hemin transporter HmuTUV and the secreted Hb-binding protein HtaA. We recently described two surface anchored proteins, ChtA and ChtC, which also bind hemin and Hb. ChtA

Hollow iron-silica nanoshells for enhanced high intensity focused ultrasound.

Alexander Liberman et al.

The Journal of surgical research, 190(2), 391-398 (2014-06-29)

High intensity-focused ultrasound (HIFU) is an alterative ablative technique currently being investigated for local treatment of breast cancer and fibroadenomas. Current HIFU therapies require concurrent magnetic resonance imaging monitoring. Biodegradable 500 nm perfluoropentane-filled iron-silica nanoshells have been synthesized as a sensitizing

Radiation-induced alterations in synaptic neurotransmission of dentate granule cells depend on the dose and species of charged particles.

V N Marty et al.

Radiation research, 182(6), 653-665 (2014-11-18)

The evaluation of potential health risks associated with neuronal exposure to space radiation is critical for future long duration space travel. The purpose of this study was to evaluate and compare the effects of low-dose proton and high-energy charged particle

Non transferrin bound iron (NTBI) in acute leukemias throughout conventional intensive chemotherapy: kinetics of its appearance and potential predictive role in infectious complications.

Angelo Belotti et al.

Leukemia research, 39(1), 88-91 (2014-12-02)

We analyzed appearance of non transferrin bound iron (NTBI) in 30 transplant eligible patients with acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL) during conventional chemotherapy treatment program and evaluated possible relationship with transfusional body iron intake, iron parameters

Effects of solution chemistry on arsenic(V) removal by low-cost adsorbents.

Yuru Wang et al.

Journal of environmental sciences (China), 25(11), 2291-2298 (2014-02-21)

Natural and anthropogenic arsenic (As) contamination of water sources pose serious health concerns, especially for small communities in rural areas. This study assessed the applicability of three industrial byproducts (coal fly ash, lignite, and green waste compost) as the low-cost

Modified Fenton oxidation of diesel fuel in arctic soils rich in organic matter and iron.

Mary K Sherwood et al.

Chemosphere, 113, 56-61 (2014-07-30)

Modified Fenton (MF) chemistry was tested in the laboratory to treat three diesel fuel-contaminated soils from the Canadian arctic rich in soil organic matter (SOM) and Fe oxides. Reactors were dosed with hydrogen peroxide (HP), and treatment was compared in

Treatment of steam-assisted gravity drainage water using low coagulant dose and Fenton oxidation.

Ahmad Al-As'ad et al.

Environmental technology, 35(13-16), 1630-1638 (2014-06-25)

The use of coagulation and Fenton oxidation was studied for total organic carbon (TOC) and silica removal from steam-assisted gravity drainage (SAGD) water at 800C and two different concentrations replicating the stream feeding the warm lime softening unit having 675

Corrosion of iron by iodide-oxidizing bacteria isolated from brine in an iodine production facility.

Satoshi Wakai et al.

Microbial ecology, 68(3), 519-527 (2014-05-28)

Elemental iodine is produced in Japan from underground brine (fossil salt water). Carbon steel pipes in an iodine production facility at Chiba, Japan, for brine conveyance were found to corrode more rapidly than those in other facilities. The corroding activity

Effects of 2,3-dimercaptosuccinic acid-coated Fe3O4 nanoparticles on genes in two mouse cell lines.

Yingxun Liu et al.

Journal of biomedical nanotechnology, 10(8), 1574-1587 (2014-07-16)

To evaluate the effects of iron oxide nanoparticles on genes from different cell lines in this study, mouse macrophage RAW264.7 and hepatocyte Hepa1-6 cell lines were treated with DMSA-coated Fe3O4 nanoparticles. Two doses were used, 50 microg/mL and 100 microg/mL

Biochemistry. Fishing for peroxidase protons.

John T Groves et al.

Science (New York, N.Y.), 345(6193), 142-143 (2014-07-12)

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